Green Synthesis of Hyperbranched Polyglycerol at Room Temperature

Mohammadifar, Ehsan; Bodaghi, Ali; Dadkhahtehrani, Abbas; Kharat, Ali Nemati; Adeli, Mohsen; Haag, Rainer

doi:10.1021/acsmacrolett.6b00804

Cited by 45 publications

(44 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…On the other hand, glycidol is a strained monomer with high reactivity toward ROPs. For example, it can be even polymerized at room temperature by Lewis or Bronsted acids . Therefore, copolymerization of glycidol and γ‐butyrolactone can results in copolymers with high glycerol/ γ‐butyrolactone ratio .…”

Section: Resultsmentioning

confidence: 99%

“…DB of the polymer was 0.43, which was less than hyperbranched polyglycerols synthesized by anionic ROP and close to the DB of polyglycerols synthesized by cationic polymerizations. This could be due to the cationic character of polymerization, which increased L 1,4 units as well as linear oligobutyrolactone fragments in the backbone of polyglycerols . Molecular weight and PDI of the synthesized PGOB was investigated by GPC.…”

Section: Resultsmentioning

confidence: 99%

“…Characterizations including FT‐IR, NMR, GPC, DLS, and MALDI‐TOF are performed according to reported procedures in the literature …”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Synthesis of boronic acid‐functionalized poly(glycerol‐oligoγ‐butyrolactone): Nano‐networks for efficient electrochemical sensing of biosystems

Hatamvand

Shams

Mohammadifar

et al. 2019

J. Polym. Sci. Part A: Polym. Chem.

Self Cite

View full text Add to dashboard Cite

Despite the outstanding properties of hyperbranched polyglycerols such as biocompatibility and multifunctionality, enough attention has not been paid to the synthesis of their functional copolymers. This problem has limited the structural diversity of hyperbranched polyglycerols and hampers further developments and their practical usage. In this work, butyrolactone segments were incorporated into the backbone of polyglycerols by one‐pot ring‐opening copolymerization of a mixture of glycidol and γ‐butyrolactone in the presence of tin(II) 2‐ethylhexanoate. Poly(glycerol‐oligoγ‐butyrolactone)s were then crosslinked by 2,5‐thiophenediylbisboronic acid to obtain polymeric nanonetworks with 140 nm average size. Afterwards, the gold electrode was modified by the polymeric nano‐networks, and it was used for the determination of glucose, glycated hemoglobin, and Escherichia coli in phosphate buffer solution (pH = 9.0) through cyclic voltammetry and impedance spectroscopic. Taking advantage of the straightforward synthesis, cheap precursors and multifunctionality of poly(glycerol‐oligoγ‐butyrolactone)s, they could be used for real‐time sensing of a wide range of biosystems. © 2019 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2019, 57, 1430–1439

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Synthesis of boronic acid‐functionalized poly(glycerol‐oligoγ‐butyrolactone): Nano‐networks for efficient electrochemical sensing of biosystems

Hatamvand

Shams

Mohammadifar

et al. 2019

J. Polym. Sci. Part A: Polym. Chem.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Recently Mohammadifar et al, reported the reaction of cationic polymerization at room temperature and solvent free to obtain polyglycerol, the polymerization is classified as green polymerization, in this type of polymerization, citric acid participates as a donor of proton, promoting polymerization, it was reported that this type of polymerization does not require a purification process which indicates that the process is very sustainable, these types of polymers may be potential candidates for biomedical applications [62].…”

Section: Polymermentioning

confidence: 99%

Applications of Carboxylic Acids in Organic Synthesis, Nanotechnology and Polymers

Sáenz‐Galindo¹,

López²,

Duran³

et al. 2018

Carboxylic Acid - Key Role in Life Sciences

View full text Add to dashboard Cite

Carboxylic acids are versatile organic compounds. In this chapter is presented a current overview of the use of carboxylic acids in a different area as organic synthesis, nanotechnology, and polymers. The application carboxylic acids in these areas are: obtaining of small molecules, macromolecules, synthetic or natural polymers, modification surface of nanoparticles metallic, modification surface of nanostructure such as carbon nanotubes and graphene, nanomaterials, medical field, pharmacy, etc. Carboxylic acids can be natural and synthetic, can be extracted or synthesized, presented chemical structure highly polar, active in organic reactions, as substitution, elimination, oxidation, coupling, etc. In nanotechnology, the use of acid carboxylic as surface modifiers to promote the dispersion and incorporation of metallic nanoparticles or carbon nanostructure, in the area of polymer carboxylic acids present applications such monomers, additives, catalysts, etc. The purpose of this chapter is to emphasize the importance of carboxylic acids in different areas, highlighting the area of organic synthesis, nanotechnology and polymers and its applications.

show abstract

“…Hydroxy-terminated hyperbranched polyether (HTHP) is a novel polymeric material, containing a large number of terminal hydroxyl groups [35,36,37]. Due to its excellent biocompatibility, HTHP is widely employed in biological materials, adhesives, etc.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Novel pH-Tunable Thermoresponsive Hydroxyl-Terminated Hyperbranched Polyether

et al. 2019

View full text Add to dashboard Cite

In this study, a new pH-tunable thermoresponsive hydroxyl-terminated hyperbranched polyether (HTHP 2) was successfully prepared via a one-pot cationic polymerization technique and postmodification. In the first step, hydroxyl-terminated hyperbranched polyether containing double bonds (HTHP 1) were synthesized. Then, through thiol-ene “click” reaction, pH-responsive carboxyl groups were introduced to the target polymer of HTHP 2. The products were characterized via Fourier-transform infrared spectra (FTIR), nuclear magnetic resonance (NMR), and size-exclusion chromatography-multiangle laser light scattering (SEC-MALLS). Moreover, dynamic light scattering (DLS) and UV–Vis spectroscopy was employed to study the pH- and thermoresponsiveness in detail. Results showed that HTHP 2 possessed typical pH-controllable thermoresponsive behavior. By regulating the solution pH value range 3.0–5.4, LCST of HTHP 2 could be changed from 12.8 to 68.0 °C. Meanwhile, the cell viabilities of A549 cells were more than 80% for in vitro cytotoxicity tests of HTHP 2, suggested that HTHP 2 polymers are of good biocompatibility for up to 24 h.

show abstract

Green Synthesis of Hyperbranched Polyglycerol at Room Temperature

Cited by 45 publications

References 33 publications

Synthesis of boronic acid‐functionalized poly(glycerol‐oligoγ‐butyrolactone): Nano‐networks for efficient electrochemical sensing of biosystems

Synthesis of boronic acid‐functionalized poly(glycerol‐oligoγ‐butyrolactone): Nano‐networks for efficient electrochemical sensing of biosystems

Applications of Carboxylic Acids in Organic Synthesis, Nanotechnology and Polymers

Synthesis of Novel pH-Tunable Thermoresponsive Hydroxyl-Terminated Hyperbranched Polyether

Contact Info

Product

Resources

About