The green synthesis of zinc oxide nanoparticles (ZnO NPs) using plant extracts has been receiving tremendous attention as an alternative to conventional physical and chemical methods. The Lamiaceae plant family is one of the largest herbal families in the world and is famous for its aromatic and polyphenolic biomolecules that can be utilised as reducing and stabilising agents during the synthesis of ZnO NPs. This review will go over the synthesis and how synthesis parameters affect the Lamiaceae-derived ZnO NPs. The Lamiaceae-mediated ZnO NPs have been utilised in a variety of applications, including photocatalysis, antimicrobial, anticancer, antioxidant, solar cells, and so on. Owing to their optical properties, ZnO NPs have emerged as potential catalysts for the photodegradation of organic dyes from wastewater. Furthermore, the low toxicity, biocompatibility, and antibacterial activity of ZnO against various bacteria have led to the application of ZnO NPs as antibacterial agents. Thus, this review will focus on the application of Lamiaceae-mediated ZnO NPs for the photodegradation of organic dyes and antibacterial applications.