Green Synthesis of Noble Metal of Platinum Nanoparticles from Ocimum sanctum (Tulsi) Plant- Extracts

Prabhu, Nagesh; Gajendran, T.

doi:10.9790/264x-0301107112

Cited by 23 publications

(6 citation statements)

References 6 publications

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“…This support is most likely to be globules of the green tea. A similar effect has also been observed in the synthesis of other metallic NPs by green chemistry methods . In the SAED patterns, platinum‐specific planes with a regular structure (face centered cubic [fcc]) were indexed (Figure a3, b3).…”

Section: Resultssupporting

confidence: 83%

Synthesis method‐dependent photothermal effects of colloidal solutions of platinum nanoparticles used in photothermal anticancer therapy

Depciuch

Stec

Maximenko

et al. 2020

Applied Organom Chemis

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One of the most common anticancer therapies is photothermal therapy (PTT). The effectiveness of PTT depends on the photosensitizer being a molecule which is toxic for the cancer cells after electromagnetic wave irradiation. Therefore, a simulation of PTT was performed in this work on two colon cancer cells (SW480 and SW620) using platinum nanoparticles (Pt NPs). Interestingly, in the literature the dependence between the synthesis method and the photothermal properties of Pt NPs was not discussed. Consequently, in this paper, we evaluated the photothermal properties of Pt NPs synthesized by two different methods: polyol (PtI NPs) and green chemistry (PtII NPs). Scanning transmission electron microscopy revealed that the size of both Pt NPs obtained was 2 nm, the NPs were not agglomerated, and that the PtII NPs were distributed on green tea supports. The selected area electron diffraction and X‐ray diffraction analysis confirmed the crystallinity of both types of Pt NPs. Fourier‐transform infrared (FTIR) spectrum of the PtII NPs showed interactions between the NPs and stretching modes for C=O groups from flavonoids and polyphenols. Therefore, these chemical compounds could be responsible for reducing Pt4+ ions to Pt0. Moreover, the 3‐(4,5‐dimethylthiazol‐2‐yl)‐5‐(3‐carboxymethoxyphenyl)‐2‐(4‐sulfophenyl)‐2H‐tetrazolium (MTS) assay showed that the PtII NPs exhibited 10% and 20% better cytotoxicity effect on SW480 and SW620 cells, than PtI NPs. The viability of cancer cells decreased when Pt NPs were used in PTT. The highest percentage of dead cells (82%) was observed for PtII NPs and 650‐nm laser irradiation. FTIR and Raman spectroscopy showed structural changes induced by both Pt NPs and laser irradiation of cells in the range corresponding to levels of DNA, phospholipids, proteins, and lipids. Moreover, the calculated photothermal conversion efficiency showed that the value of this parameter is around 35%, regardless of the synthesis method and used wavelengths.

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Section: Resultssupporting

confidence: 83%

Synthesis method‐dependent photothermal effects of colloidal solutions of platinum nanoparticles used in photothermal anticancer therapy

Depciuch

Stec

Maximenko

et al. 2020

Applied Organom Chemis

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“…PtNPs gets synthesized through reduction of platinum metal precursors such as platinum chloride and chloroplatinic acid. [64,65] The precursor is dissolved in organic or aqueous liquid material. Synthesis of solid NPs from dissolved precursor is carried out by introducing a reducing agent which leads to a chemical conversion step.…”

Section: Chemical Methodsmentioning

confidence: 99%

Usage of Platinum Nanoparticles for Anticancer Therapy over Last Decade: A Review

Pawar

Sahoo

Verma

et al. 2021

Part & Part Syst Charact

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The quest for new functional nanomaterials is one of the defining purposes of nanoscience and nanotechnology. A large number of metal nanoparticles (NPs) are extensively exploited for biomedical applications. Metal NPs, in particular platinum NPs (PtNPs), possess remarkable properties that make them a potential candidate as a diagnostic or therapeutic agent. Due to potential technological interest over the last decade, PtNPs have attracted much attention in the field of anticancer research. PtNPs, when conjugated with many functionalizing agents such as polymers, ligands, drugs, peptides, and surfactants, exhibit improved targeting and reduced cytotoxic effects in various cancers. The PtNPs conjugated with folic acid, graphene oxide, and iron NPs are gained more attention due to their stability, large surface area, and reduced toxicity. To achieve this goal, PtNPs are co‐loaded with drugs or other modalities that offer an opportunity for multimodal activity in the frame of treating cancer types focusing on breast, blood, lung, ovarian, skin, liver, etc. However, a review of PtNPs’ function in diagnosis and treatment is still lacking. In this review, the effectiveness of PtNPs toward inducing and elevating death of the cancerous cells proving its delivery approaches and antitumor nature, concluding with future perspectives, are summarized.

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“…The first synthesis was achieved at 100 • C for 1 h [65]. In contrast, the second one was completed at room temperature by stirring for about 20 min, and the ratio of the plant extract to Pt(IV) ions was kept at 1:9 [66]. The phytosynthesis of PtNPs was done using ethanolic extract of (Punica granatum) pomegranate crusts as the reducing agent.…”

Section: Green Synthesis Of Ptnps Using Plant Extractsmentioning

confidence: 99%

“…Two studies reported the green synthesis of PtNPs using Ocimum sanctum (Tulsi) leaves extract yielding irregular structured NPs with sizes 23 and 2 nm, respectively [65,66]. PtNPs were characterized by FT-IR, XRD, energy dispersive absorption X-Ray, SEM, and TEM.…”

Section: Characterization and Biological Activities Of Ptnps Prepared Using Plant Extractsmentioning

confidence: 99%

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Platinum Nanoparticles: Green Synthesis and Biomedical Applications

et al. 2020

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Platinum nanoparticles (PtNPs) have superior physicochemical properties and great potential in biomedical applications. Eco-friendly and economic approaches for the synthesis of PtNPs have been developed to overcome the shortcomings of the traditional physical and chemical methods. Various biogenic entities have been utilized in the green synthesis of PtNPs, including mainly plant extracts, algae, fungi bacteria, and their biomedical effects were assessed. Other biological derivatives have been used in the synthesis of PtNPs such as egg yolk, sheep milk, honey, and bovine serum albumin protein. The green approaches for the synthesis of PtNPs have reduced the reaction time, the energy required, and offered ambient conditions of fabrication. This review highlights the state-of-the-art methods used for green synthesis of PtNPs, synthesis parameters, and their reported biomedical applications.

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Green Synthesis of Noble Metal of Platinum Nanoparticles from Ocimum sanctum (Tulsi) Plant- Extracts

Cited by 23 publications

References 6 publications

Synthesis method‐dependent photothermal effects of colloidal solutions of platinum nanoparticles used in photothermal anticancer therapy

Synthesis method‐dependent photothermal effects of colloidal solutions of platinum nanoparticles used in photothermal anticancer therapy

Usage of Platinum Nanoparticles for Anticancer Therapy over Last Decade: A Review

Platinum Nanoparticles: Green Synthesis and Biomedical Applications

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