Green synthesis of non-isocyanate hydroxyurethane and its hybridization with carboxymethyl cellulose to produce films

Oladzadabbasabadi, Nazila; Abraham, Billu; Ghasemlou, Mehran; Ivanova, Elena P.; Adhikari, Benu

doi:10.1016/j.ijbiomac.2024.133617

International Journal of Biological Macromolecules

2024

DOI: 10.1016/j.ijbiomac.2024.133617

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Green synthesis of non-isocyanate hydroxyurethane and its hybridization with carboxymethyl cellulose to produce films

Nazila Oladzadabbasabadi,

Billu Abraham,

Mehran Ghasemlou

et al.

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Cited by 5 publications

References 42 publications

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Multifunctional Carbon Dots In Situ Confined Hydrogel for Optical Communication, Drug Delivery, pH Sensing, Nanozymatic Activity, and UV Shielding Applications

Marvi,

Das,

Jafari

et al. 2025

Adv Healthcare Materials

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Inspired by the emerging potential of photoluminescent hydrogels, this work unlocks new avenues for advanced biosensing, bioimaging, and drug delivery applications. Carbon quantum dots (CDs) are deemed particularly promising among various optical dyes, for enhancing polymeric networks with superior physical and chemical properties. This study presents the synthesis of CDs derived from Prunella vulgaris, a natural plant resource, through a single‐step hydrothermal process, followed by their uniform integration into hydrogel matrices via an in situ free radical graft polymerization. The resulting CD‐integrated hydrogels exhibit multifunctionality in biomedical applications, featuring a diffusion‐controlled drug release mechanism, permit concurrent delivery of photoluminescent CDs and therapeutic agents, enabling real‐time monitoring over 32 h. In addition, these hydrogels function as a broad‐range optical pH sensor (pH 3–11), provide robust ultraviolet (UV) shielding, and demonstrate nanozyme‐like peroxidase activity. Critically, biocompatibility tests confirm their non‐cytotoxicity toward fibroblast cells, establishing these hydrogels as promising candidates for diverse biomedical applications. These include advanced wound dressings that monitor the healing process and detect infection through pH sensing, and promote healing through the nanozymatic activity, all while maintaining a moist wound microenvironment. These hydrogels demonstrate exceptional suitability for advanced smart drug delivery, effective UV‐blocking, and as innovative platforms for in vivo sensing and bioimaging.

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Multifunctional Carbon Dots In Situ Confined Hydrogel for Optical Communication, Drug Delivery, pH Sensing, Nanozymatic Activity, and UV Shielding Applications

Marvi,

Das,

Jafari

et al. 2025

Adv Healthcare Materials

View full text Add to dashboard Cite

show abstract

Development of an Innovative Reinforced Food Packaging Film Based on Corn Starch/Hydroxypropyl Methylcellulose/Nanocrystalline Cellulose Incorporated with Nanogel Containing Quercetin

Al-Naymi,

Oladzadabbasabadi,

Karim

et al. 2024

Food Bioprocess Technol

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Investigating the impact of thymol/ɤ-cyclodextrin concentrations on the properties of electrospun PLA/PVP nanofibers for packaging applications

Mohammad,

Oladzadabbasabadi,

Kareem

et al. 2024

Colloids and Surfaces A: Physicochemical and Engineering Aspect

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Green synthesis of non-isocyanate hydroxyurethane and its hybridization with carboxymethyl cellulose to produce films

Cited by 5 publications

References 42 publications

Multifunctional Carbon Dots In Situ Confined Hydrogel for Optical Communication, Drug Delivery, pH Sensing, Nanozymatic Activity, and UV Shielding Applications

Multifunctional Carbon Dots In Situ Confined Hydrogel for Optical Communication, Drug Delivery, pH Sensing, Nanozymatic Activity, and UV Shielding Applications

Development of an Innovative Reinforced Food Packaging Film Based on Corn Starch/Hydroxypropyl Methylcellulose/Nanocrystalline Cellulose Incorporated with Nanogel Containing Quercetin

Investigating the impact of thymol/ɤ-cyclodextrin concentrations on the properties of electrospun PLA/PVP nanofibers for packaging applications

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