Green Synthesis of Polyherbal Silver Nanoparticles from Rosa Gallia officinalis, Citrus sinensis and Solanum tuberosum Extract for antioxidant Potency

Abstract

Skin ageing is due to the combination of natural, largely genetically programmed and environmentally modulated changes which occur in the body system due to free radical damage. Silver Nanoparticle (AgNPs), were prepared by chemical reduction using green synthesis and they were evaluated for particle size in nanometer, zeta potential in millivolt, surface morphology by scanning electron microscopy (SEM) and percent entrapment efficiency. The polyphenols were quantified by chromatographic techniques and the antioxidant activity measured spectrophotometrically by DPPH (2,2 Diphenyl 1 picrylhydrazyl) assay. According to this study AgNPs showed a least particle size of 145.4±2.4nm, maximum zeta potential of -39.1±2.4 mV with desired polydispersity index of 0.358±0.02, the amount of polyphenols loaded in AgNPs was found to be 87.23±2.54%. Maximum phenolic content was found in F1 as 65.21 ± 3.721 mg equivalent GAE/g of extract. On comparing the IC50 values, F1 and F5 exhibited the lowest and highest values respectively. Therefore, F1 possesses higher DPPH radical scavenging potential.

Advanced Material Against Human (Including Covid‐19) and Plant Viruses: Nanoparticles As a Feasible Strategy

“…Antiviral drug entrapment efficiency (EE) and loading capacity (LC) of SLNPs vary due to lipid and surfactant (and co-surfactant when present) composition, nevertheless the smaller size of SLNPs is indicated as a crucial to obtain higher EE and LC, due to the SLNPs higher surface area. [29][30][31][32][33][34][35] One of the most interesting PLGA-NPs property is their highly tailorable nature, with a considerable described methodology produce PLGANPs capable to carry lipophilic or hydrophilic molecules of different sizes and structural motifs, and assures its protection. In addition, PLGA-NPs surfaces are readily modifiable.…”