Functional Polysaccharides for Biomedical Applications 2019
DOI: 10.1016/b978-0-08-102555-0.00008-x
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Green synthesis of polysaccharide-based inorganic nanoparticles and biomedical aspects

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Cited by 21 publications
(13 citation statements)
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References 160 publications
(211 reference statements)
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“…They can stabilize and control the size of MNPs during the synthesis process, prevent further agglomeration, and provide additional chemical stability. They possess various binding sites, which enables attachment to the metal surface, creating a stable organic-inorganic network [ 171 ]. However, despite the outstanding biocompatibility and biodegradability properties of polysaccharides per se and the apparent lack of side effects, cytotoxicity studies must be performed when associated with MNPs.…”
Section: Safety Issues Of Mnps and The Role Of Polysaccharidesmentioning
confidence: 99%
“…They can stabilize and control the size of MNPs during the synthesis process, prevent further agglomeration, and provide additional chemical stability. They possess various binding sites, which enables attachment to the metal surface, creating a stable organic-inorganic network [ 171 ]. However, despite the outstanding biocompatibility and biodegradability properties of polysaccharides per se and the apparent lack of side effects, cytotoxicity studies must be performed when associated with MNPs.…”
Section: Safety Issues Of Mnps and The Role Of Polysaccharidesmentioning
confidence: 99%
“…After cellular death or exocytosis, the synthetic polymers cannot be entirely degraded, resulting in their buildup in the tissue [ 40 ]. It is possible to hydrolyze or enzymatically break down biodegradable natural polysaccharides into oligosaccharides, di- or monosaccharides, which are then absorbed via biochemical processes [ 41 ]. Due to their inherent food properties, dietary polysaccharides are generally considered safe (GRAS) and have excellent biocompatibility and biodegradability.…”
Section: Introductionmentioning
confidence: 99%
“…There are two main strategies for synthesis of titanium nanoparticles: conventional methods and green synthesis. Physical and chemical production of nanoparticles have some limitations which cause environmental concerns, such as the use of toxic reducing and stabilizing agents, extreme reaction conditions, and low productivities 5–8 . Because of these challenges, nanoparticles produced by conventional methods may not be appropriate for biotechnological and biomedical applications 6 .…”
Section: Introductionmentioning
confidence: 99%
“…Physical and chemical production of nanoparticles have some limitations which cause environmental concerns, such as the use of toxic reducing and stabilizing agents, extreme reaction conditions, and low productivities. [5][6][7][8] Because of these challenges, nanoparticles produced by conventional methods may not be appropriate for biotechnological and biomedical applications. 6 Thus, in recent years, biological reduction of metal ions to metal nanoparticles has been developed as a novel green synthesis technique.…”
mentioning
confidence: 99%
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