Green synthesis of silver nanoparticles by Chrysanthemum morifolium Ramat. extract and their application in clinical ultrasound gel

Abstract

Eco-friendly green synthesis with plant extracts plays a very important role in nanotechnology, without any harmful chemicals. In this report, the synthesis of water-soluble silver nanoparticles was developed by treating silver ions with Chrysanthemum morifolium Ramat. extract at room temperature. The effect of the extract on the formation of silver nanoparticles was characterized by ultraviolet and visible absorption spectroscopy, X-ray diffraction, transmission electron microscopy, and Fourier transform infrared spectroscopy. The ultraviolet and visible absorption spectroscopy results show a strong resonance centered on the surface of silver nanoparticles (AgNP) at 430 nm. The Fourier transform infrared spectroscopy spectral study demonstrates Chrysanthemum morifolium Ramat. extract acted as the reducing and stabilizing agent during the synthesis. The X-ray diffraction analysis confirmed that the synthesized AgNP are single crystallines, corresponding with the result of transmission electron microscopy. Water-soluble AgNP, with an approximate size of 20 nm-50 nm were also observed in the transmission electron microscopy image. The bactericidal properties of the synthesized AgNP were investigated using the agar-dilution method and the growth-inhibition test. The results show the AgNP had potent bactericidal activity on Staphylococcus aureus and Escherichia coli, as well as a strong antibacterial activity against gram-negative bacteria, as compared to gram-positive bacteria with a dose-dependent effect, thus providing a clinical ultrasound gel with bactericidal property for prevention of cross infections.

New procedure to synthesize silver nanoparticles and their interaction with local anesthetics

“…On the other hand, colloidal systems containing AgNPs could have various medical applications, based on the well-known bactericidal properties of silver. [12][13][14][15][16]46 Our preliminary investigations on these AgNPs adsorbed on hydroxyapatites in fact showed high antimicrobial activity. Since the reagents used are entirely nontoxic, this nanotechnology might be readily integrated for biological applications.…”

“…8 Silver NPs (AgNPs) are of great interest for their various applications in microelectronics, photonics and photocatalysis, surface-enhanced Raman scattering, [9][10][11] and as antibacterial and antimicrobial agents. [12][13][14][15][16] Bioconjugates of AgNPs have also been prepared and their self-assembly investigated. [17][18][19][20] Various methods, among them biogenic methods, 12,[14][15][16][20][21][22][23][24][25][26][27] have been used for the synthesis of AgNPs.…”

“…[12][13][14][15][16] Bioconjugates of AgNPs have also been prepared and their self-assembly investigated. [17][18][19][20] Various methods, among them biogenic methods, 12,[14][15][16][20][21][22][23][24][25][26][27] have been used for the synthesis of AgNPs. Glucose is well known for reducing Ag + to Ag in alkaline solutions, and this method was also used…”

Green Synthesis of Silver Nanoparticles using Mediterranean Cypress (<i>Cupressus sempervirens</i>) Leaf Extract

“…Bioactive compounds from plants are the other source for natural reducing and capping agents. Bioactive compounds from various herbs and plants such as Piper longum, Crataegus douglasii, Nephelium lappaceum, Lippia citriodora, Plukenetia volubilis, Chrysanthemum morifolium, Medicago sativa, Sterculia foetida, Cinnamon zeylanicum, Alcea rosea, Zataria multiflora, Matricaria chamomilla and black tea were used for synthesis of AgNPs in a sustainable manner (Cruz et al, 2010;Vivekanandhan et al, 2014;Reddy et al, 2014;Ghaffari-Moghaddam and Hadi-Dabanlou, 2014;Kumar et al, 2015;He et al, 2013;Lukman et al, 2011;Rajasekharreddy and Rani, 2014;Sathishkumar et al, 2009;Ebrahiminezhad et al, 2016b;2016e;2016c).…”

Synthesis, optimization, and characterization of silver nanoparticles from Acinetobacter calcoaceticus and their enhanced antibacterial activity when combined with antibiotics

“…1,2 There is an interest in the synthesis of nanomaterials because they exhibit AgNPs can be synthesized by chemical, 18 physical, 19,20 or biological routes involving plants 8,17,21,22 or microorganisms. [23][24][25][26][27][28] Biological synthesis is preferred nowadays because these methods are safe, cheap, eco-friendly, and do not involve any toxic substrate or by-product.…”