Green synthesis of starch-capped Cu₂O nanocubes and their application in the direct electrochemical detection of glucose

Abstract

Starch-capped Cu2O nanocubes were used as an active electrochemical element to directly detect glucose.

Nanostructured Titanium Dioxide Surfaces for Electrochemical Biosensing

“…As it was mentioned in the introduction, metal oxides of Cu, Zn, Ni or Fe are other good surface options for biosensors, and their functionalization has also been studied [9][10][11][12]. It is important to notice that many of them share with TiO 2 the potential for surface functionalization through the reactivity of surface bound -OH groups, which act as covalent anchoring points to various functional groups (silanes, phosphonates, carboxylates, catechols, alkenes/alkynes and amines) of specific molecules [71].…”

“…Sensors based on nanostructured metal oxides of metals such as Cu, Zn, Ni, Fe and Ti have advantages as lower limits of detection, wide linear range, reproducibility and stability. CuO-based electrochemical biosensors have been developed for glucose detection with good stability and sensitivity [9][10][11][12]. The main advantages of using CuO nanomaterials are precise surface area, good electrochemical activity and the ability to stimulate electron transfer reactions at lower potentials.…”

Carbohydrate polymer-supported metal and metal oxide nanoparticles for constructing electrochemical sensors

“…93 The Ag NP-locust bean gum composite showed the highest sensitivity and lowest detection limit towards glucose compared to other carbohydrate polymer-based nanocomposites such as Au NP-dextran 136 and Cu 2 O NP-starch NCs. 95 Latex (natural rubber)…”

“…[181][182][183] Cu 2 O-starch NC as a modified carbon paste electrode has been used as an electrochemical sensor for the assessment of glucose using the CV technique based on its oxidation. 95 Additionally, a CoNP/starch/CPE was used for the detection of paracetamol based on its oxidation via twoelectron and two-proton transfer. 184…”

Copper–Oxygen Compounds and Their Reactivity: An Eye-Guided Undergraduate Experiment

“…In this way, many methods have been described for obtaining copper­(I) oxide from copper­(II) salts. In the more classical syntheses (not electrochemical or hydrothermal), maybe the most used reductants are sugars (making use of the well-known behavior of Benedict’s reagent or Fehling’s solution), − but other reductants such as ascorbic acid, , hydrazine, sodium borohydride, or hydroxylamine have also been employed. Among these synthetic methods, the simplest ones, and therefore the easiest to implement in an undergraduate laboratory, typically lead to brick-red Cu 2 O nanoparticles, whose color is reminiscent of Cu 0 metal itself.…”