Green synthesis of starch-mediated CuO nanoparticles: preparation, characterization, antimicrobial activities and in vitro MTT assay against MCF-7 cell line

Alishah, Hossein; Pourseyedi, Shahram; Ebrahimipour, S. Yousef; Mahani, Saeed Esmaili; Rafiei, Nahid

doi:10.1007/s12210-016-0574-y

Cited by 83 publications

(33 citation statements)

References 42 publications

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“…XRD pattern exhibited no extra peaks, indicating the green CuO NPs were highly purified. Using the Debye-Scherrer formula, the crystal size of CuO NPs of the highest peak at 2 theta = 38.66° (111) was found to be 20.76 nm which fairly smaller than CuO NPs (90.0, 52.0, and 59.8 nm) synthesized by wet chemical precipitation [49], starch extract [50], and flower extract methods, respectively [36].…”

Section: Xrd Examination Of Cuo Npsmentioning

confidence: 97%

Biofabrication of highly pure copper oxide nanoparticles using wheat seed extract and their catalytic activity: A mechanistic approach

Buazar

Sweidi

Badri

et al. 2019

Green Processing and Synthesis

111

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A facile novel green methodology is presented for the synthesis of highly stable and well-dispersed copper oxide nanoparticles using aqueous wheat seed extract. Under optimal reaction conditions, the wheat seed extract-derived electron-rich biomolecules were functioned as a reducing and capping/ stabilizing agent. The ultraviolet-visible absorption peak at 300 nm was confirmed the formation of copper oxide nanoparticles. Fourier-transform infrared spectroscopy analysis determined Cu–O bonds in nanosample, indicating the active role of functional groups in the wheat seed extract in bio-reduction of Cu cations. X-ray diffraction pattern results demonstrated the monoclinic structure of highly pure biosynthesized copper oxide nanoparticles with a crystallite size of 20.76 nm. The stability of copper oxide nanoparticles was confirmed after 3 months’ storage of product with no sedimentation or suspension. Transmission electron microscopy results showed the spherical shape of nano-particle with an average size of 22 ± 1.5 nm. X-ray photo-electron spectroscopy analyses revealed only copper and oxygen elements in the sample, confirming the purity of copper oxide nanoparticles. Bio-assisted copper oxide nanoparticles demonstrated significant catalytic efficiency and reusability toward 4-nitrophenol removal by an average of 97.6% from aqueous solutions after successive 5 days’ exposure to UV irradiation.

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Section: Xrd Examination Of Cuo Npsmentioning

confidence: 97%

Biofabrication of highly pure copper oxide nanoparticles using wheat seed extract and their catalytic activity: A mechanistic approach

Buazar

Sweidi

Badri

et al. 2019

Green Processing and Synthesis

111

View full text Add to dashboard Cite

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“…With the increase in the concentration of the sample, the ROS production also increases which in turn explains the oxidative damage caused to the cancer cells [24]. Thus, a greater number of NPs easily enter the cancer cells and generate free radicals which are responsible for the destruction of the cancer cells [25].…”

Section: Evaluation Of Cytotoxicity and Antibacterial Activities Of Tmentioning

confidence: 99%

Eco-synthesis and characterization of titanium nanoparticles: Testing its cytotoxicity and antibacterial effects

Eisa

Almansour

Alnaim

et al. 2020

Green Processing and Synthesis

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In recent years, green synthesis of nanoparticles has been the cornerstone of development of nanotechnology and its applications, as it emphasizes on promoting environmental sustainability. The aim of the present study was to investigate the potential health benefits of the green-synthesized titanium nanoparticles (TiO2NPs). TiO2NPs were synthesized using titanium(iv) isopropoxide and lupin bean extract. The synthesized particles were characterized to assess the average particle size by dynamic light scattering, and X-ray diffraction method was used to study the crystalline nature. The average particle size recorded was 9.227 nm with a polydispersity index (PDI) of 0.382. The morphology of the particles was assessed by scanning electron microscope and transmission electron microscopy which showed varied shapes of the nanoparticles, uniform spherical and crystallite rod shaped. Further, the cytotoxic efficacy of the nanoparticles was assessed against the breast cancer (MCF-7) cell line using 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromidefor (MTT) assay. The antibacterial activity of the nanoparticles was evaluated against clinical pathogens via the disc diffusion assay. The key findings showed that the TiO2NPs exhibited potent cytotoxicity against the MCF-7 cell line with an IC50 of 41.1 µg. It also showed profound antibacterial activity. Thus, the synthesized nanoparticles could have potential biomedical applications owing to their therapeutic efficacy.

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“…The morphological changes were assessed using Hoechst 33258 staining assay, and results obtained revealed that the greenly synthesized nanoparticles exhibited higher cytotoxic that the chemically synthesized CuONPs [168]. Alishah et al [169] reported the synthesis of CuONPs (mean size of 54 nm) using starch extracted from Solanum tuberosum. It was revealed via MTT assay that the synthesized CuONPs demonstrated the anticancer activity against MCF-7 cell line.…”

Section: Applications Of Metallic Nanoparticles As Anticancer Agentsmentioning

confidence: 99%

Biomedical Applications of Green Synthesized-Metallic Nanoparticles: A Review

Lateef

Elegbede

Akinola

et al. 2019

PAJOLS

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Advances in the field of nanoscience and nanotechnology to modulate materials at nanoscale level has continued to have great impact on different disciplines of science and engineering as well as agriculture and medical fields. The surge in the utilization of benign and non-toxic biomolecules to engineer enhanced biocompatible nanomaterials has contributed to a large extent to the applications of nanomaterials in healthcare; an emerging sub-discipline termed nanomedicine. Among the several nanomaterials that have been produced, metallic nanoparticles occupy prime position owing to their optical, catalytic and biological characteristics. These nanoparticles, which are of different types existing singly as mono-metallic nanoparticles or in two or more metals as alloys have found extremely useful applications as antimicrobial, antioxidant, anticancer, antidiabetic, anticoagulant and thrombolytic agents amongst others. In this review, an attempt is made to project the different applications of green synthesized metallic nanoparticles in diverse areas of biomedicine, including the discussion of issues of toxicity and prospects of nanotechnology in biomedical field.

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Green synthesis of starch-mediated CuO nanoparticles: preparation, characterization, antimicrobial activities and in vitro MTT assay against MCF-7 cell line

Cited by 83 publications

References 42 publications

Biofabrication of highly pure copper oxide nanoparticles using wheat seed extract and their catalytic activity: A mechanistic approach

Biofabrication of highly pure copper oxide nanoparticles using wheat seed extract and their catalytic activity: A mechanistic approach

Eco-synthesis and characterization of titanium nanoparticles: Testing its cytotoxicity and antibacterial effects

Biomedical Applications of Green Synthesized-Metallic Nanoparticles: A Review

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