Green synthesis of ZnO nanoparticles in grape extract: Their application as anti-cancer and anti-bacterial

Hussein, Baraa Y.; Mohammed, Ahmed Mishaal

doi:10.1016/j.matpr.2021.03.729

Cited by 31 publications

(8 citation statements)

References 36 publications

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“…Unregulated and rapid development of malignant tumors, which can aggregate to form a growth or propagate all through the body and cause abnormal growth, is a hallmark of many disorders. It can continue until the organism perishes 31 . Consuming a lot of fruits and vegetables can help to reduce the occurrence of cancer since several naturally occurring components in human diet have been identified as potential chemo-preventive agents.…”

Section: Discussionmentioning

confidence: 99%

High throughput biochemical profiling, and functional potential analysis for valorization of grape peduncles

Akbar

Gul

Hussain

et al. 2023

Sci Rep

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Vitis vinifera L., commonly known as grape is a major fruit crop in the world. Grapes seem to confer health benefits due to their chemical components, biological and antioxidant activities. The present study is conducted to evaluate the biochemical constituents, antioxidant, and antimicrobial potential of ethanolic grape peduncles (EGP) extract. The result of phytochemical analysis revealed the presence of various phytochemicals such as flavonoid, tannin, carbohydrates, alkaloids, cardiac glycoside, phenol, steroid, terpenoids, quinones and anthraquinones. Furthermore, total phenolic content (TPC) and total flavonoid contents (TFC) were 7.35 ± 0.25 mg GAE/g (Gallic Acid Equivalent per gram) and 29.67 ± 0.13 mg QE/g (Quercetin Equivalent per gram) respectively. DPPH (2, 2-diphenyl-1-picrylhydrazyl) free radical scavenging assay revealed IC50 = 159.3 μg/mL. The antibacterial and antifungal study disclosed that the extract was highly potent against Salmonella typhi with maximum zone of inhibition of 27.2 ± 1.60 mm and Epidermophyton floccosum with 74 ± 1.81% inhibition. The extract was analyzed for its cytotoxicity and antileishmanial activity and showed no activity against HeLa cell line and promastigotes of Leishmania major. Elements Fe, Mn, Ni, Pb and Cd were determined by atomic absorption spectroscopy and approximately 50 compounds were identified by Gas Chromatography-Mass Spectrometry (GC–MS). Current work suggest that grape peduncles can be a promising source of bioactive medicinal component.

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Section: Discussionmentioning

confidence: 99%

High throughput biochemical profiling, and functional potential analysis for valorization of grape peduncles

Akbar

Gul

Hussain

et al. 2023

Sci Rep

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“…Green synthesis or biosynthesis, as an alternative in obtaining NPs, involves the use of plant metabolites, microorganisms, and algae. Obtaining ZnO NPs, as an inorganic semiconductor, leads to the formation of amphoteric particles, insoluble in water (Hussein and Mohammed 2021 ).…”

Section: Methods Used For Zno Nanostructure Preparation and Their Cha...mentioning

confidence: 99%

ZnO nanostructured matrix as nexus catalysts for the removal of emerging pollutants

Matei,

Șăulean,

Râpă

et al. 2023

Environ Sci Pollut Res

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Water pollution stands as a pressing global environmental concern, elevating the significance of innovative, dependable, and sustainable solutions. This study represents an extensive review of the use of photocatalytic zinc oxide nanoparticles (ZnO NPs) for the removal of emerging pollutants from water and wastewater. The study examines ZnO NPs’ different preparation methods, including physical, chemical, and green synthesis, and emphasizes on advantages, disadvantages, preparation factors, and investigation methods for the structural and morphological properties. ZnO NPs demonstrate remarkable properties as photocatalysts; however, their small dimensions pose an issue, leading to potential post-use environmental losses. A strategy to overcome this challenge is scaling up ZnO NP matrices for enhanced stability and efficiency. The paper introduces novel ZnO NP composites, by incorporating supports like carbon and clay that serve as photocatalysts in the removal of emerging pollutants from water and wastewater. In essence, this research underscores the urgency of finding innovative, efficient, and eco-friendly solutions for the removal of emerging pollutants from wastewater and highlights the high removal efficiencies obtained when using ZnO NPs obtained from green synthesis as a photocatalyst. Future research should be developed on the cost–benefit analysis regarding the preparation methods, treatment processes, and value-added product regeneration efficiency. Graphical Abstract

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“…Ayrıca mantarın yapısında bulunan organik bileşiklerinden kaynaklandığı düşünülen C-O gerilmesine ait titreşim pikleri sırasıyla 1026, 1033 ve 1071 cm -1 'de kaydedilmiştir. Bileşik a ve b'nin FT-IR spektrumlarında Agaricus bisporus' un yapısında bulunan flavanoidler, terpenoidler ve polifenoller gibi -OH grubu açısından zengin bileşiklerin varlığının gözlenmemesinin nedeni, metal iyonu ile kompleks oluşumudur [13]. Agaricus bisporus destekli ZnO NP sentezi sırasında indirgeyici ajan ve stabilizatör olarak görev alan biyomolekülleri tespit edebilmek için mantar ekstraktının sulu ve susuz ortamdaki FT-IR spektrumları alınmıştır.…”

Section: Bulgular Ve Tartişma a Ft-ir Anali̇zi̇unclassified

Agaricus bisporus Ekstraktı Kullanılarak ZnO Nanopartiküllerinin Yeşil Sentezi: Yapısal Karakterizasyonu ve Biyolojik Aktivitelerinin İncelenmesi

BEKEM

Durmuş

Dalmaz

et al. 2023

Düzce Üniversitesi Bilim Ve Teknoloji Dergisi

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Nanoteknolojinin ilginç yönlerini keşfetmek adına son yıllarda birbirinden farklı birçok çalışma yapılmaktadır. Nanomalzeme üretiminin hızlı gelişimi, çok çeşitli alanlarda metal oksit (ZnO) uygulamalarını da beraberinde getirmiştir. Çinko oksit nanopartikülleri (ZnO NP), ticari kullanım için mekanik veya kimyasal olarak elde edilebilir. Ancak, bu tekniklerin ortaya çıkardığı çevre sorunları bir hayli dikkat çekmiştir. Günümüzde, ZnO NP’nin yeşil sentezi, çevre sorunlarını azaltmayı amaçlayan araştırma alanında özellikle ilgi görmektedir. Bu yeşil yaklaşımda, bitki özü, mikroorganizma, mantar ve alg gibi doğal bazlı malzemeler, biyoaktif fitokimyasallardaki zenginleşmeleri nedeniyle biyo-indirgeyici ve biyo-stabilizatör olarak kullanılmaktadır. Bu çalışmada, ZnO NP farklı çinko tuzları ile doğal bir ürün olan mantar ekstraktı (Agaricus bisporus) kullanılarak sentezlenmiştir. Elde edilen ZnO NP X-ışını kırınımı (XRD), Fourier dönüşümü kızılötesi spektroskopisi (FT-IR), Taramalı elektron mikroskobu (SEM) analizi, Enerji dağılımlı X-ışını analizi (EDX) ile karakterize edildi. Son olarak ZnO NP’nin bakteri ve funguslara karşı antimikrobiyal aktiviteleri kuyu difüzyon yöntemi ile ölçülerek sonuçlar kaydedildi.

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Green synthesis of ZnO nanoparticles in grape extract: Their application as anti-cancer and anti-bacterial

Cited by 31 publications

References 36 publications

High throughput biochemical profiling, and functional potential analysis for valorization of grape peduncles

High throughput biochemical profiling, and functional potential analysis for valorization of grape peduncles

ZnO nanostructured matrix as nexus catalysts for the removal of emerging pollutants

Agaricus bisporus Ekstraktı Kullanılarak ZnO Nanopartiküllerinin Yeşil Sentezi: Yapısal Karakterizasyonu ve Biyolojik Aktivitelerinin İncelenmesi

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