Green-Synthesized Silver Nanoparticles and Their Potential for Antibacterial Applications

Abstract

The prevalence of infectious diseases is becoming a worldwide problem, and antimicrobial drugs have long been used for prophylactic and therapeutic purposes, but bacterial resistance has creating serious treatment problems. The development of antibiotic resistance makes scientists around the world to seek new drugs that would be more effective. The use and search for drugs obtained from plants and other natural products have increased in recent years. It is well known that silver and its compounds have strong antibacterial activity. Silver, compared to the other metals, shows higher toxicity to microorganisms, while it exhibits lower toxicity to mammalian cells. The progress in the field of nanotechnology has helped scientists to look for new ways in the development of antibacterial drugs. Silver nanoparticles (AgNPs) are interesting for their wide range of applications, e.g. in pharmaceutical sciences, which include treatment of skin diseases (e.g. acne and dermatitis) and other infectious diseases (e.g. post-surgical infections). Various antibacterial aids, such as antiseptic sprays, have also been developed from AgNPs. In this chapter, we have focused on various synthesis methodologies of AgNPs, antibacterial properties, and the mechanism of action.

Green Synthesis of Silver Nanoparticles with Antibacterial Activity Using Various Medicinal Plant Extracts: Morphology and Antibacterial Efficacy

“…There are various methods for the synthesis of AgNPs, belonging to chemical [ 11 ], physical [ 12 , 13 ] and biological ones [ 14 , 15 , 16 ]. Furthermore, AgNPs can be prepared in a sustainable manner, which is beneficial due to its simplicity, low cost and eco-friendly manner, making it harmless for both human and animal health [ 17 , 18 , 19 , 20 ].…”

Green synthesized plant-based silver nanoparticles: therapeutic prospective for anticancer and antiviral activity

“…This method is a good alternative to conventional methods of nanoparticles synthesis. The product formed using this method is more stable with the desired shape and size [ 18 , 19 ].…”

Exogenous Production of Silver Nanoparticles by Tephrosia apollinea Living Plants under Drought Stress and Their Antimicrobial Activities

“…The antimicrobial activity of AgNPs was tested widely against several pathogenic bacteria. It has been established that AgNPs possess strong antimicrobial activity against both Gram-positive and Gram-negative bacteria [55]. However, previous investigations have not provided a definite answer on whether Gram-negative [56] or Gram-positive bacteria [57,58] are more sensitive to AgNPs.…”