Green Tea, A Medicinal Food with Promising Neurological Benefits

Abstract

: Neurological disorders and their sequelae, as of the widespread and critical humans complications, affect the body's nervous systems, organ functions, and behaviors. According to WHO, neurological disorders are currently predicted to affect more than one billion people globally. It is well-established that complementary medicine is one of the high accepted interventions that could have been considered for the management of neurological ailments. The current review aimed to compile a frame from all the crucial data reporting the investigation on the conspicuous intervention of green tea (made of Camellia sinensis) and related lead compounds (especially l-theanine, epigallocatechin-3-gallate, epicatechin-3-gallate, epicatechin, and epigallocatechin) for their neurological activities, mechanisms of action, and clinical properties. According to the documents, green tea exhibits antidepressant, anti-neurodegenerative (e.g., anti-Parkinson and anti-Alzheimer), as well as neuroprotective effects. Chief among them, for offering novel work, it is worth focusing on several related assessments with great attention to more extensive standardized clinical trials, and subsequently more in-depth pharmacokinetic studies to safely introduce this beneficial medicinal food as a neuro-effective agent.

Mycotoxins Detection and Fungal Contamination in Black and Green Tea by HPLC-Based Method

“…These substances can also reduce the formation of free radicals in the body which have an important role in aging and precursing many forms of diseases. Tea also contains many dietary components, including vitamin E, C, fluoride, and potassium [ 4 , 5 ]. Mycotoxins are secondary fungal metabolites that produced by specific strains of mold (fungi) which are famous as potential top priority human's health hazard.…”

Does ( −)-epigallocatechin-3-gallate protect the neurotoxicity induced by bisphenol A in vivo?

“…Within this view, herbal medications that have been scientifically proven to be effective antioxidants and neuroprotective agents may have a protective impact against BPAinduced neurotoxicity. Green tea, which has been widely investigated for its protective effect against neurotoxicity and neuronal damage, was one of the most popular herbal antioxidants (Akbarialiabad et al 2021). Furthermore, green tea has been demonstrated to significantly lower BPA-induced oxidative stress on erythrocytes in vitro and in silico studies (Suthar et al 2014).…”

Therapeutic Potential of Natural Compounds from Herbs and Nutraceuticals in Alleviating Neurological Disorders: Targeting the Wnt Signaling Pathway

“…176 L-Theanine, an amino acid found naturally in Camellia sinensis and some other plant extracts, has numerous health benefits, including anti-inflammatory, antioxidant, neuroprotective, metabolic regulation, anticancer, immunomodulatory, and antiobesity effects. 177 For example, L-theanine reduces oxidative damage by reducing ROS synthesis and increasing antioxidant enzyme activity. 178 Previous studies have shown that L-theanine has antidepressive, antineurodegenerative, and neuroprotective effects.…”