Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans

Venables, Michelle C.; Hulston, Carl J.; Cox, Hannah R; Jeukendrup, Asker E.

doi:10.1093/ajcn/87.3.778

Cited by 243 publications

(238 citation statements)

References 21 publications

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“…Since MCP-1 is a major chemoattractive chemokine for macrophage, it could be assumed that its reduction is probably related to the reduction in macrophage and oral glucose tolerance test were similar in both groups, independently of white tea intake. This result is in agreement with most studies on glucose homeostasis (NOMURA et al, 2008;VENABLES et al, 2008) after green tea intake. In those studies, in which a beneficial effect of green tea in reducing glucose was observed, the amount of green tea in the diet was about 3%, six times higher than that offered in the present study (KHAN et al, 2007), and the experimental period was 16 weeks, twice as much time of the present study (BOSE et al, 2008).…”

Section: Discussionsupporting

confidence: 93%

White tea (Camellia sinensis) extract reduces oxidative stress and triacylglycerols in obese mice

et al. 2012

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White tea is an unfermented tea made from young shoots of Camellia sinensis protected from sunlight to avoid polyphenol degradation. Although its levels of catechins are higher than those of green tea (derived from the same plant), there are no studies addressing the relationship between this tea and obesity associated with oxidative stress.The objective of this study was to evaluate the effect of white tea on obesity and its complications using a diet induced obesity model. Forty male C57BL/6 mice were fed a high-fat diet to induce obesity (Obese group) or the same diet supplemented with 0.5% white tea extract (Obese + WTE) for 8 weeks. Adipose tissue, serum lipid profile, and oxidative stress were studied. White tea supplementation was not able to reduce food intake, body weight, or visceral adiposity. Similarly, there were no changes in cholesterol rich lipoprotein profile between the groups. A reduction in blood triacylglycerols associated with increased cecal lipids was observed in the group fed the diet supplemented with white tea. White tea supplementation also reduced oxidative stress in liver and adipose tissue. In conclusion, white tea extract supplementation (0.5%) does not influence body weight or adiposity in obese mice. Its benefits are restricted to the reduction in oxidative stress associated with obesity and improvement of hypertriacylglycerolemia.

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Section: Discussionsupporting

confidence: 93%

White tea (Camellia sinensis) extract reduces oxidative stress and triacylglycerols in obese mice

et al. 2012

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“…It also may promote the phosphorylation of insulin-signaling proteins and enhance insulin activity. [20][21][22] Wolfram et al 23 indicated that EGCG beneficially improved glucose and lipid metabolism in H4IIE cells and enhanced glucose tolerance in models of diabetes. Green tea extract also could increase fat metabolism and lipolysis in healthy humans.…”

Section: Introductionmentioning

confidence: 99%

“…Green tea extract also could increase fat metabolism and lipolysis in healthy humans. 22 Another study provided evidence that green tea promoted glucose metabolism in healthy humans and produced an antihyperglycemic effect in diabetic mice. 24 A population-based, case-control study by Polychronopoulos et al 25 reported that tea consumption could reduce levels of fasting blood glucose in nonobese elderly people.…”

Section: Introductionmentioning

confidence: 99%

Tea Consumption and Risk of Type 2 Diabetes: A Meta-Analysis of Cohort Studies

Jing

Han

et al. 2009

J GEN INTERN MED

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BACKGROUND: Tea consumption has been extensively studied in relation to various diseases, several epidemiologic studies have been performed to investigate the association of tea consumption with type 2 diabetes; however, the results of these studies were not entirely consistent. OBJECTIVE:To conduct a meta-analysis of studies that assessed the association of tea consumption and the risk of type 2 diabetes. RESEARCH DESIGN AND METHODS:We performed a systematic literature search through November 2008 in PUBMED, MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews. The search was limited to Englishlanguage studies. Studies were excluded if they were type 1 diabetes, animal studies. Nine cohort studies were identified by two authors, and summary relative risks (RRs) were calculated using a random-effects model. RESULTS:We identified nine cohort studies, including 324,141 participants and 11,400 incident cases of type 2 diabetes with follow-up ranging from 5 to 18 years. The summary adjusted RR did not show that tea consumption was associated with a reduced type 2 diabetes risk (RR, 0.96; 95% confidence interval (CI), 0.92-1.01). Evidence from the results of our stratified analyses revealed that tea consumption ≥4 cups per day (RR, 0.8; 95% CI, 0.7-0.93) might play a role in the prevention of type 2 diabetes. However, no statistically significant association was observed for sex and the follow-up durations stratified between tea consumption and type 2 diabetes. CONCLUSIONS:This meta-analysis indicates that tea consumption ≥4 cups per day may lower the risk of type 2 diabetes.KEY WORDS: type 2 diabetes; tea; meta-analysis.

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“…A recent cross-over placebo controlled study (Venables et al, 2008) reported an increase of fat oxidation by 17% after a supplement containing various green tea polyphenols and 366 mg EGCG (but not caffeine) compared with the control group. It is the first evidence that a single catechin, namely EGCG, has the potential to moderately affect fat oxidation.…”

Section: Prevention Of Metabolic Syndrome (Mets) and Cardiovascular Dmentioning

confidence: 99%

Tea and human health: biomedical functions of tea active components and current issues

Chen

Zhi

2015

J. Zhejiang Univ. Sci. B

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Originating in China, tea and tea planting have spread throughout the world since the middle of the Tang dynasty. Now people from 160 countries in the world are accustomed to tea drinking. A brief history of tea's medicinal role in China and its spread to the world are introduced. The effectiveness of tea active components and tea drinking on major human diseases, including cancer, metabolic syndrome, cardiovascular disease, and neurodegenerative diseases, is discussed. Also presented are some related issues, such as the bioavailability of tea active components, the new formulations of tea polyphenols, and the safety for consumers of dietary supplements containing tea polyphenols.

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Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans

Abstract: Acute GTE ingestion can increase fat oxidation during moderate-intensity exercise and can improve insulin sensitivity and glucose tolerance in healthy young men.

Cited by 243 publications

References 21 publications

White tea (Camellia sinensis) extract reduces oxidative stress and triacylglycerols in obese mice

White tea (Camellia sinensis) extract reduces oxidative stress and triacylglycerols in obese mice

Tea Consumption and Risk of Type 2 Diabetes: A Meta-Analysis of Cohort Studies

Tea and human health: biomedical functions of tea active components and current issues

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