Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomized controlled trials

Abstract

The analysis of eligible studies showed that the administration of green tea beverages or extracts resulted in significant reductions in serum TC and LDL-cholesterol concentrations, but no effect on HDL cholesterol was observed.

Tea Consumption and Longitudinal Change in High‐Density Lipoprotein Cholesterol Concentration in Chinese Adults

“…Consistent with findings from animal studies36 and clinical studies,8 we observed that green tea had a stronger effect than black tea on plasma HDL‐C concentrations. It is thought that polyphenols in tea (eg, phenols and catechins) could account for its benefits in lipid metabolism via antioxidation and inhibition of lipid absorption 6, 11, 37, 38.…”

“…However, in the participants at highest cardiovascular disease risk, a nonsignificant trend was observed for a positive association between tea consumption and HDL‐C concentrations, whereas no such trend was observed in the healthy participants 7, 8, 9. Trials conducted in participants with chronic conditions including obesity, hypertension, or other metabolic symptoms and durations >12 weeks reported significant increases in HDL‐C concentrations resulting from tea consumption 11, 13, 29, 30.…”

“…Meta‐analyses that have pooled clinical trials reported that there was no significant effect of green or black tea and HDL‐C concentrations 7, 8, 9. However, in the participants at highest cardiovascular disease risk, a nonsignificant trend was observed for a positive association between tea consumption and HDL‐C concentrations, whereas no such trend was observed in the healthy participants 7, 8, 9.…”

“…Clinical trials have reported that tea beverages lower total cholesterol (TC) and low‐density lipoprotein cholesterol concentrations 7, 8, 9. However, findings on the potential effects of tea on high‐density lipoprotein cholesterol (HDL‐C) are mixed.…”

High performance liquid chromatography tandem mass spectrometry dual extraction method for identification of green tea catechin metabolites excreted in human urine

“…Samples were vortexed for 10 sec before the addition of 500 µL ice cold ethyl 9 acetate. Samples were then vortexed for 30 sec and placed on ice for 2 min before centrifugation at 10 17,000 g (4 ºC) for 2 min. The extract (supernatant) was placed in a new microcentrifuge tube on ice.…”