Cultural products constitute a significant portion of global trade, and understanding their export patterns can shed light on economic trends, trade dynamics, and market opportunities. This study conducted the spatio-temporal analysis of exports of cultural products, exploring the relationship between various influencing factors and their impact on the spatial distribution of these exports. Leveraging a diverse dataset encompassing 55 BRI countries for the period of 2005–2022, this research employs advanced spatial analysis techniques, including spatial autocorrelation and spatial regression models, to examine the spatial patterns and determinants of exports if cultural product exports. Moreover, this study delves into the multifaceted determinants affecting the spatial distribution of these exports. The findings of this study reveal significant spatio-temporal variations in the exports of cultural products. Spatial autocorrelation analysis indicates the presence of spatial clustering, suggesting that regions with high cultural product exports tend to be geographically close to each other. The spatial regression models further identify several key factors like economic development, productive capacities, cultural tourism, information development and human capital influence the spatial distribution of these exports. The findings of the study reveal that there is strong spatial relationship for exports of cultural products in BRI countries. The findings of this research contribute valuable insights for policymakers, businesses, and stakeholders regarding a deeper comprehension of the driving forces behind the spatial distribution of these cultural products, facilitating informed decision-making processes to optimize strategies for promoting and sustaining the trade of cultural products in an increasingly interconnected world.