The history of the science of the stars (astronomy and astrology) in fourteenth-century Byzantium is significantly intertwined with the implications of theological and philosophical controversies. A less-explored astronomical text authored by the fourteenth-century Byzantine scholar Theorodos Meliteniotes (ca. 1320–1393 CE) provides new historical factors toward a historiography of the differences between scientific and theological discourses, their development in the transition to early modern times, and the different historical developments of science in the worlds of the Eastern and Western Churches.