Groin dissection

Spratt, John S.

doi:10.1002/(sici)1096-9098(200004)73:4<243::aid-jso13>3.0.co;2-w

Cited by 45 publications

(45 citation statements)

References 18 publications

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“…Spratt reported transecting numerous major afferent lymphatics, as well as large segments of lymphatics during groin dissection. 3 Therefore, we thought that the difference in volumes of drain discharge could represent the extent of We speculated that the wider dissection of the skin flap needed in S-shaped incisions than straight incisions necessitates excess transection of the lymphatic vessels. Therefore, we surmised that performing an S-shaped incision results in collection of lymphatic fluid in the local area, causing prolonged wound drainage.…”

Section: Discussionmentioning

confidence: 99%

“…2 Regional lymphadenectomy in the groin, as devised by Basset in 1912, is performed for the staging and treatment of patients with malignant neoplasms of the skin in the lower extremities and perineum. 3 The decision to perform this operation entails an assessment of indications, risks, and benefits, [3][4][5] and the incidence of complications has been studied in various series. [6][7][8][9][10][11] Several investigators have reported low operative morbidity, whereas others reached an opposite conclusion.…”

Section: Introductionmentioning

confidence: 99%

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Operative Morbidity Associated with Groin Dissections

et al. 2004

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Operative Morbidity Associated with Groin Dissections

et al. 2004

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“…Sixty-two patients had partial amputation of the penis and the other 11 had total amputation. All patients had a bilateral inguinal lymphadenectomy; the borders of the inguinal dissection included 2 cm above the inguinal ligament superiorly, the apex of the femoral triangle inferiorly, the adductor longus medially and the sartorius muscles laterally [16]. All superficial and deep inguinal LNs within the field were removed.…”

Section: Methodsmentioning

confidence: 99%

The prognostic significance of p53, Ki‐67, epithelial cadherin and matrix metalloproteinase‐9 in penile squamous cell carcinoma treated with surgery

et al. 2007

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OBJECTIVE To evaluate the prognostic significance of p53, Ki‐67, epithelial cadherin (E‐cadherin) and matrix metalloproteinase‐9 in primary penile cancer, as the presence of lymph node metastasis and long‐term survival are hard to define in penile squamous cell carcinoma. PATIENTS AND METHODS Paraffin‐embedded primary tumour samples were obtained from 73 Chinese patients who had penile amputation and regional lymphadenectomy. The expression of molecular markers was determined by immunohistochemistry. Logistic regression was used to identify factors associated with lymph node metastasis, and a Cox proportional‐hazards model was used to measure cancer‐specific survival (CSS). RESULTS Thirty (41%) patients presented with nodal disease and the 3‐year CSS rate for all patients was 72%. Lymph node metastasis was significantly correlated with tumour stage, histological grade, lymphatic and vascular embolization, and the expression of p53, Ki‐67 and E‐cadherin. By multivariate analysis, tumour embolization and the expression of p53 were independent predictors of metastasis. Survival analysis showed that the expression of p53 was an independent prognostic factor for CSS. In stage T1 tumours, high expression of p53 was significantly associated with metastasis and poor survival. CONCLUSION Lymphatic and vascular embolization, and p53 immunoreactivity, are helpful in establishing the probability of lymph node metastasis. The expression of p53 is an independent predictor of CSS in Chinese patients with penile cancer. In stage T1 tumours, p53 staining is an important variable determining the prognosis and treatment outcome.

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“…In 1948 Baronofsay, described technique of Sartorius muscle transposition. In 1912, Basset, First discribed the aim of the surgical procedure is to remove en bloc the deep and superficial lymph nodes of the inguinal region (17) . Additionally, an ilioinguinal, or radical, groin dissection may be performed, where the inguinal, iliac, and obturator nodes are removed in continuity (18) .…”

Section: Surgical Approach Historical Prospectivementioning

confidence: 99%