Grossly Abnormal Cervix: Evidence for Using Colposcopy in the Absence of Squamous Intraepithelial Lesion by Conventional Papanicolau Test

Dasari, Papa

doi:10.1089/gyn.2010.0035

Cited by 7 publications

(7 citation statements)

References 5 publications

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“…It is a very common for the gynaecologists who work in tertiary care institutes in the developing countries to get referrals from practitioners and peripheral health centres for patients with a clinical diagnosis of an "unhealthy cervix " . 1 The Papanicolaou's (Pap) smear is the primary screening tool for Cervical Intra-epithelial Neoplasia (CIN) and for invasive cancer of the uterine cervix. Recently, the assumed accuracy of the Pap smear, which was found to be 80% to 95% for detecting CIN and early invasive cancer, was questioned.…”

Section: Introductionmentioning

confidence: 99%

A Comparison of Pap Smear, Colposcopy and Colposcopy Directed Biopsy in Evaluation of Unhealthy Cervix

Savitha¹,

Sapna²

2015

jemds

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Section: Introductionmentioning

confidence: 99%

A Comparison of Pap Smear, Colposcopy and Colposcopy Directed Biopsy in Evaluation of Unhealthy Cervix

Savitha¹,

Sapna²

2015

jemds

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“…Clinical diagnosis of an "unhealthy cervix" was based on any one or a group of chronic conditions affecting the uterine cervix including hypertrophied cervix, erosions, nabothian cysts, bleeds on touch, polyps and erosions. 7 Women who were not willing to participate, pregnant females, visible growth on cervix, acute PID, type 2 or 3 Transformation zone on colposcopy, immunocompromised subjects, or who have previously undergone any treatment for cervical intraepithelial neoplasia (CIN), or having any other malignancy were excluded from the study. 41 women were lost to follow up and only 99 women who had high grade colposcopy (Swede Score≥5) 12 were enrolled for further analysis and cytology of these 99 women were simultaneously evaluated and compared with colposcopy after hisopathological examination of tissue.…”

Section: Methodsmentioning

confidence: 99%

“…It has been felt that apart from cervical smears cytology, colposcopy should be offered as diagnostic method in all patients with unhealthy cervix with clinical findings of hypertrophied cervix, presence of erosions, nabothian cysts and cervix that bleeds on touch. 7 An unhealthy cervix or grossly abnormal cervix can harbour premalignant cervical lesions or invasive carcinoma even when the cytology test is negative. 8 Due to poor sensitivity of Pap smear, symptomatic women with negative smear requires further evaluation by colposcopy and high grade colposcopy then should be taken histopathology.…”

Section: Introductionmentioning

confidence: 99%

Role of Colposcopy in Evaluation of Abnormal Cytology a Tertiary Care Centre Experience

Sachan¹,

Shukla²,

Sachan³

et al. 2020

IJMEDPH

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Background: Evidence for using colposcopy in the absence of a squamous intraepithelial lesion on conventional cytology has important position in cervical cancer screening. Aim of this study to evaluate sensitivity, specificity and diagnostic accuracy of colposcopy and cytology in unhealthy cervix to know role of colposcopy in concurrent use with cytology or replacing to cytology at tertiary centre experience. Methods: Prospective study was carried out over a period of one year, in patients attending Gynaecology OPD, King George's Medical University, Lucknow, Uttar Pradesh. After informed consent and ethical clearance from institutional ethics committee, total 664 diagnostic colposcopy were performed in women presenting with gynaecological complaint. These women were called for concurrent colposcopy and pap smear. 41 women were lost to follow up, only 623 women were subjected for concurrent colposcopy and cytology. 99 women who had high grade colposcopy with Swede score ≥5 underwent colposcopic guided biopsy and tissue were sent for histopathological examination and cytology of same patients were compared for analysis. Results: Mean age of women was 42.68±11.69 years and mean age of consummation of marriage 20.94±3.21years. Cervical erosion was most common finding (41.4%) followed by hypertrophy of cervix (33.3%) and cervix bleeds on touch (17.2%). 24.14% (n=7) women with ASCUS cytology had high grade HPE (CIN2 +) while 42.3% (n=11) women with LSIL had high grade HPE (CIN2 +). Taking ASCUS and above as cutoff , the sensitivity, specificity, of Pap smear was 97.8%, 14.6% and diagnostic accuracy was 55.3%. For overall analysis of Colposcopy Swede Score at ≥5, colposcopy was 100% sensitive and 41.2% specific and diagnostic accuracy was 69.7%. At swede score ≥7, colposcopy was 64.6% sensitive and 100% specific and diagnostic accuracy was 82.8%. Conclusion: Colposcopy has good sensitivity and specificity as compared to cytology and can be used in evaluation of abnormal or controversial cytology to obtain better outcome.

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“…It is very common for the gynaecologists who work in tertiary care institutes in developing countries to get referrals from practitioners and peripheral health centres for patients with a clinical diagnosis of an "unhealthy cervix." [1] For Cervical Intra-Epithelial Neoplasia (CIN) and invasive cancer of the uterine cervix, Papanicolaou's (Pap) smear is the primary screening tool. The assumed accuracy of the pap smear, which was recently found to be 80% to 95% for detecting CIN and early invasive cancer was questioned.…”

Section: Introductionmentioning

confidence: 99%

Colposcopic Evaluation of Clinically Unhealthy Cervix

Akter¹,

Nasreen²,

Islam³

et al. 2021

JGO

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Cervical cancer is the commonest malignancy found amongst Bangladeshi women and the third most common cancer in the world. New cases of invasive cervical cancer are diagnosed over 5,00,000 annually worldwide. For Cervical Intra-Epithelial Neoplasia (CIN) and for invasive cancer of the uterine cervix, Papanicolaou's (Pap) smear is the primary screening tool. The Pap smear accuracy, which was recently assumed found to be 80% to 95% for detecting CIN and early invasive cancer, was questioned. Colposcopy and directed biopsy are needed to clarify the clinically unhealthy cervix in women. This study was conducted to evaluate the role of colposcopy in identifying. The aim of the study was to assess the role of colposcopy of the unhealthy cervix to localize the lesions and to obtain biopsies from the selected areas. This prospective observational study conducted from January 2016 to December 2016 in the Department of Obstetrics and Gynaecology, Sikder Medical College, Dhaka including 104 patients who were aged between 25-65 years with clinically unhealthy cervix, were exposed to a colposcopic evaluation. All the patients underwent colposcopic-directed biopsies. The biopsies were taken from the act white areas and the iodine negative areas. Among 104 patients, 49 (47.1%) were in the age group of 25-34 years. In the parity, 97 (93.3%) 0-4 child, 61 (58.7%) were married before 18 years of age. 17 (16.35%) had normal colposcopic findings. The colposcopic evaluation and the guided biopsy were successful in detecting abnormalities in 26 out of 31 cases. The incidence of CIN 1 and CIN2, 3 were found colposcopically and histologically 33.65%, 24.04%, and 11.54%, respectively. In the present study, the sensitivity of colposcopy was 83.33%. Both the neoplastic and the non-neo-plastic ones, colposcopy was found to be useful in understanding the morphology of the cervical lesions and this would very helpful in planning their management in the future.

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Grossly Abnormal Cervix: Evidence for Using Colposcopy in the Absence of Squamous Intraepithelial Lesion by Conventional Papanicolau Test

Cited by 7 publications

References 5 publications

A Comparison of Pap Smear, Colposcopy and Colposcopy Directed Biopsy in Evaluation of Unhealthy Cervix

A Comparison of Pap Smear, Colposcopy and Colposcopy Directed Biopsy in Evaluation of Unhealthy Cervix

Role of Colposcopy in Evaluation of Abnormal Cytology a Tertiary Care Centre Experience

Colposcopic Evaluation of Clinically Unhealthy Cervix

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