Ground-glass opacity of the lung parenchyma: a guide to analysis with high-resolution CT.

Engeler, Christopher E.; Tashjian, Joseph H.; Trenkner, Stephen W.; Walsh, J W

doi:10.2214/ajr.160.2.8424326

Cited by 101 publications

(51 citation statements)

References 3 publications

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“…On our correlativestudy,areasof ground glass opacity with or without irregular linear opacity or bronchial dilatation on CT repre sented pathologically the areas of interstitial thickening caused by varying degrees of in terstitial inflammation and fibrosis showing temporal uniformity [ 14,19]. Interstitial in Jardin et al [20], volume averaging of the tiny parenchymal cysts that characterize the microcystic honeycomb pattern may also lead to increased lung attenuation.…”

Section: Ct Of Nonspecific Interstitial Pneumonia With Fibrosismentioning

confidence: 56%

Nonspecific interstitial pneumonia with fibrosis: high-resolution CT and pathologic findings.

Kim¹,

Lee²,

Chung³

et al. 1998

American Journal of Roentgenology

164

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OBJECTIVE. The purposeof our studywas to describehigh-resolutionCT findingsof nonspecific interstitial pneumonia with fibrosis and to compare findings seen on CT with pathologic findings. MATERIALS AND METHODS. High-resolutionCT findingsof biopsy-provennonspecific interstitial pneumonia with fibrosis from 23 consecutive patients (one man and 22 women) were analyzed retrospectively by two chest radiologists. CT findings were compared with pathologic findings.RESULTS. The predominant high-resolution CT finding,seenin all patients,wasbilateral patchy areasof ground-glass opacity with (35%) or without (65%) areasof consolidation. Ir regular linear opacities (87%), thickening of bronchovascular bundles (65%), and bronchial dilatation (52%) were also frequently seen. Honeycombing was not seen in any patient. All parenchymal abnormalities showed subpleural predominance. Areas of ground-glass opacity with or without irregular linear opacity or bronchial dilatation on CT correspondedpathologi cally to areasof interstitial thickening causedby varying degreesof interstitial inflammation and fibrosisshowingtemporaluniformity.Areas of consolidation, seenat five biopsysites, represented the areas of bronchiolitis obliterans organizing pneumonia, foamy cell collections in alveolar spaces,or microscopic honeycombing with mucin stasis. CONCLUSION.On high-resolutionCT, nonspecificinterstitialpneumoniawith fibrosis is most commonly revealed as patchy subpleural areasof ground-glass opacity mixed with ir regular linear opacity or bronchial dilatation. These areas represent interstitial thickening caused by varying degrees of interstitial inflammation, fibrosis, or both.

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Section: Ct Of Nonspecific Interstitial Pneumonia With Fibrosismentioning

confidence: 56%

Nonspecific interstitial pneumonia with fibrosis: high-resolution CT and pathologic findings.

Kim¹,

Lee²,

Chung³

et al. 1998

American Journal of Roentgenology

164

View full text Add to dashboard Cite

show abstract

“…Actually viral pneumonia which is clinically serious can cause alveolar haemorrhage. There weren't decline in haemoglobin or haemoptysis [10]. They didn't have medical history suggesting vasculitis or immunological disease.…”

Section: Discussionmentioning

confidence: 95%

Severe Pneumonia Treated Succesfully with Levofloxacin and Oseltamivir During Flu Epidemic

Kabalak¹,

Esenkaya²

2015

Turk Thorac J

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Viral pneumonia is an important cause of community acquired pneumonias (CAP). It's not only specific to childhood period. Although immunocompromised adults are susceptible; all young and healthy adults are at risk. Viral pneumonias are usually underestimated due to lack of diagnostic modalities so a clinician must be aware of. Co-infection of viruses and bacteria is not uncommon and can be mortal especially in a flu epidemic, therefore, in the absence of diagnostic tools initiating to anti-viral treatment without delay is important.

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“…Ground-glass opacity (GGO) is a highly significant finding on high-resolution CT because it is associated with different kinds of lung diseases such as adenocarcinomas [2], bronchioloalveolar carcinoma [3], idiopathic pulmonary fibrosis and sarcoidosis [4], etc. GGO is defined as hazy increased CT attenuation of the lung without entire obscuration of the lung parenchyma within it.…”

Section: Introductionmentioning

confidence: 99%

“…Much higher frequency of malignancy was shown in lung tumor with GGO [5]. Moreover, it was reported that GGO percentage (the proportion of GGO area in a lung tumor) [2,6] and GGO spatial distribution pattern [4] are the significant prognostic factors of some lung diseases. Therefore, measuring the opacities of the lung tumor pixels with CT image is vital to the radiologic analysis of a lung cancer candidate.…”

Section: Introductionmentioning

confidence: 99%

Estimation of Ground-Glass Opacity Measurement in CT Lung Images

Zheng

Kambhamettu

Bauer

et al. 2008

Medical Image Computing and Computer-Assisted Intervention – MICCAI 2008

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Abstract. We propose to measure quantitatively the opacity property of each pixel in a ground-glass opacity tumor from CT images. Our method results in an opacity map in which each pixel takes opacity value of [0][1]. Given a CT image, our method accomplishes the estimation by constructing a graph Laplacian matrix and solving a linear equations system, with assistance from some manually drawn scribbles for which the opacity values are easy to determine manually. Our method resists noise and is capable of eliminating the negative influence of vessels and other lung parenchyma. Experiments on 40 selected CT slices of 11 patients demonstrate the effectiveness of this technique. The opacity map produced by our method is invaluable in practice. From this map, many features can be extracted to describe the spatial distribution pattern of opacity and used in a computer-aided diagnosis system.

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Ground-glass opacity of the lung parenchyma: a guide to analysis with high-resolution CT.

Cited by 101 publications

References 3 publications

Nonspecific interstitial pneumonia with fibrosis: high-resolution CT and pathologic findings.

Nonspecific interstitial pneumonia with fibrosis: high-resolution CT and pathologic findings.

Severe Pneumonia Treated Succesfully with Levofloxacin and Oseltamivir During Flu Epidemic

Estimation of Ground-Glass Opacity Measurement in CT Lung Images

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