Field experiments were carried out at Mutobus District, Kafr El-Sheikh Governorate to evaluate the efficacy of Ackocynil R (bromoxynil octanoate 32.75% EC) at 1.00 L. fed-1 , Brominal W R (bromoxynil octanoate 24% EC) at 1.00 L. fed-1 , Derby R (florasulam 7.5 %+ flumetsulam 10%) at 30 ml fed .-1 , Icopart R (pyraflufen-ethyl 2% SC) at 250 ml fed.-1 and Sinal R (metosulam 10% SC) at 40 ml fed.-1 in comparison with handweeding twice (at 21 and 42) days after sowing and untreated check (weed free) during 2017/2018 and 2018/2019 seasons on broad-leaved weeds in wheat crop. Anagallis arvensis, Beta vulgaris, Cichorium pumpilum, Medicago sativa, Rumex dentatus and Sanchus oleraceus, were the predominant weed species during the both seasons, except, Anagallis arvensis, which was found in the second season only. All predominant weeds in the experimental field were identified as broadleaved weeds. Among predominant weed species, Beta vulgaris and Medicago sativa were the most predominant during 2017/2018 and 2018/2019 seasons. Results clearly indicated that all herbicidal treatments showed significant herbicidal activity against weeds compared to the control during the two examined seasons. Among the herbicides examined, Ackocynil R and Brominal W R were the most options in controlling weeds as well as increasing yield components and grain yield in wheat crop than the other treatments.