2012
DOI: 10.1016/j.physbeh.2012.05.002
|View full text |Cite
|
Sign up to set email alerts
|

Group and individual regulation of physiology and behavior: A behavioral, thermographic, and acoustic study of mouse development

Abstract: The traditional approach to the study of thermoregulation in young animals focuses on the regulatory capacities of individuals, which, for multiparous species, risks ignoring critical aspects of the early developmental niche. Here, we examined the ontogeny of regulatory behavior in C57BL/6 mice, employing simultaneous behavioral, thermographic, and acoustic measures of groups and individual pups. Litters of mice were placed in a chamber on Postnatal Day (PND) 2, 4, or 8, in which the ambient temperature (Ta) g… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

6
65
1

Year Published

2015
2015
2022
2022

Publication Types

Select...
8

Relationship

2
6

Authors

Journals

citations
Cited by 44 publications
(72 citation statements)
references
References 69 publications
6
65
1
Order By: Relevance
“…When mouse pups are tested as a group, they tend to huddle up with littermates at low temperatures to keep warm. Under such test conditions, there is no significant difference between the numbers or the sizes (measured as perimeter) of the huddling aggregates, or ultrasonic vocalization between P4 and P8 pups [57]. Similarly in rats, thermoregulation is consistently poor up to P7 and improves significantly only afterward [58].…”
Section: Discussionmentioning
confidence: 99%
“…When mouse pups are tested as a group, they tend to huddle up with littermates at low temperatures to keep warm. Under such test conditions, there is no significant difference between the numbers or the sizes (measured as perimeter) of the huddling aggregates, or ultrasonic vocalization between P4 and P8 pups [57]. Similarly in rats, thermoregulation is consistently poor up to P7 and improves significantly only afterward [58].…”
Section: Discussionmentioning
confidence: 99%
“…We tested the hypothesis that manipulating the environment of the mouse, without changing the T a from 20°C, would alleviate the cold stress through behavioral thermoregulation (13,16). When mice are housed in groups of two or more, mice typically huddle, decrease their collective surface area, and conserve heat (21). The density of a huddle increases with a corresponding decrease in T a (21).…”
Section: Discussionmentioning
confidence: 99%
“…When mice are housed in groups of two or more, mice typically huddle, decrease their collective surface area, and conserve heat (21). The density of a huddle increases with a corresponding decrease in T a (21). Huddling confers a thermoregulatory advantage; group-housed infant mice (4 days postnatal) exhibit a delay in brown-fat-induced thermogenesis upon cold exposure but no significant long-term inhibition of BAT activity (11).…”
Section: Discussionmentioning
confidence: 99%
“…The smaller Cbx3 hypo/hypo newborns would lose heat more rapidly compared to Prlr −/− newborns because of the former's greater surface-to-volume ratio (the 'square-cube law'; Haldane 1926). Moreover, heat loss may be further compounded because, in addition to thermoregulation via BAT, thermoregulation in newborn altricial rodents has a behavioural component termed huddling (Alberts 1978;Sokoloff and Blumberg 2001;Harshaw and Alberts 2012). Huddling close to littermates is protective against the rapid heat loss that occurs during the brief exposure to cool ambient temperatures that isolated pups experience when the dam leaves the nest (Harshaw and Alberts 2012).…”
Section: Loss Of Energy Homeostasis In Cbx3 Hypo/hypo Neonatesmentioning
confidence: 99%
“…Moreover, heat loss may be further compounded because, in addition to thermoregulation via BAT, thermoregulation in newborn altricial rodents has a behavioural component termed huddling (Alberts 1978;Sokoloff and Blumberg 2001;Harshaw and Alberts 2012). Huddling close to littermates is protective against the rapid heat loss that occurs during the brief exposure to cool ambient temperatures that isolated pups experience when the dam leaves the nest (Harshaw and Alberts 2012). Notably, in a huddle of newborns there is competition between pups and pups with functional BAT thermogenesis tend to avoid contact with pups whose BAT thermogenesis is blocked (Sokoloff and Blumberg 2001).…”
Section: Loss Of Energy Homeostasis In Cbx3 Hypo/hypo Neonatesmentioning
confidence: 99%