Group B streptococci in pregnancy: New perspectives for old challenges

Stein, Richard A.

doi:10.1111/ijcp.13340

Int J Clin Pract

2019

DOI: 10.1111/ijcp.13340

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Group B streptococci in pregnancy: New perspectives for old challenges

Richard A. Stein

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2020

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Prevention of Perinatal Group B Streptococcus Infections

Fan

Tasneem

et al. 2020

Maternal-Fetal Medicine

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Group B streptococcus (GBS) is a leading cause of neonatal infection. Maternal vaginal-rectal colonization with GBS during the intrapartum period is a prerequisite for GBS early-onset disease (EOD). The obstetric measures for effective prevention of GBS EOD include universal prenatal screening by vaginal-rectal culture, correct specimen collection and processing, appropriate implementation of intrapartum antibiotic prophylaxis, and coordination with pediatric care providers. It is now recommended to universal screen GBS between 360/7 and 376/7 weeks of gestation and to identify groups of women who are eligible for intravenous intrapartum antibiotic prophylaxis as a means of preventing GBS EOD.

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Prevention of Perinatal Group B Streptococcus Infections

Fan

Tasneem

et al. 2020

Maternal-Fetal Medicine

View full text Add to dashboard Cite

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Prevalence and capsular type distribution of group B Streptococcus isolated from vagina of pregnant women in Nghe An province, Vietnam

Hanh¹,

Du²,

Hien³

et al. 2020

IJM

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Background and Objectives: Identification of GBS serotypes provides helpful information for appropriate the develop- ment of suitable vaccines; however, no reports from Vietnam have been published. This study has been performed to find the prevalence and serotypes of group B Streptococcus isolated from vagina of pregnant women in Nghe An province, Vietnam. Materials and Methods: Vaginal swabs were collected from pregnant women at 35-37 weeks of gestation at the Nghe An Obstetrics and Pediatrics Hospital, Vietnam between May 2018 and July 2019. The swabs were cultured on 5% sheep blood agar for isolation of GBS. All isolates were identified using the Gram staining, CAMP test and specific PCR. GBS strains were serotyped using the multiplex PCR assays. Results: The prevalence of vaginal GBS colonization was 9.20% of 750 participants. Among the isolates, serotypes III (39.13%) and V (31.89%) were the most frequent, followed by serotypes Ia (11.59%), VI (11.59%), Ib (2.90%), II (1.45%) and VII (1.45%), respectively. Serotypes IV, VIII and IX were not found. Conclusion: The prevalence of GBS in the Nghe An province of central Vietnam was similar to reports from other parts of the world. The predominat GBS serotypes (III, V, Ia and VI) were slightly different from those previously described from other regions around the world. The high frequency of serotype VI was a notable feature of the strains from pregnant women in Vietnam.

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Group B streptococci in pregnancy: New perspectives for old challenges

Cited by 2 publications

References 36 publications

Prevention of Perinatal Group B Streptococcus Infections

Prevention of Perinatal Group B Streptococcus Infections

Prevalence and capsular type distribution of group B Streptococcus isolated from vagina of pregnant women in Nghe An province, Vietnam

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