“…8 In this communication, we report the syntheses of spirocyclic 3,5-difluorocyclohexa-2,5-dienone derivatives such as 3 as model com-pounds for controlling the spiro centers and for investigating the group selectivity of reactions with various nucleophiles or cyclopenta-1,3-diene. 9 The synthesis of the spirocyclic 3,5-difluorocyclohexa-2,5-dien-1-one 3 is shown in Scheme 1. First, an aryllithium derivative, prepared from the iodo compound 5 10 through lithium-halogen exchange, was treated with the difluorobenzaldehyde 4 11 to give adduct 6 in 96% yield.…”