Group-Specific Component (Gc): Subtypes in the Finnish Population

Abstract

The group-specific component (Gc) subtypes were determined in 575 adult Finns by immunoblotting after isoelectric focusing in agarose gel. The gene frequencies were Gc^1s= 0.661, Gc^1F= 0.139 and Gc²=0.200. This material included one rare allele, a more acidically focusing Gc 2 (named Gc 2A18). The phenotypes of 200 mother-child pairs studied were in accordance with the three-allelic mode of inheritance. An apparent mother-child incompatibility observed during routine paternity testing is reported.

Gc Subtypes in Finns, Swedes and Swedish Lapps

“…The gene frequencies observed in the Finnish population were close to those found in an earlier investi gation from Finland by Lukka et al [1986).…”