Group-specific Multi-allergen Sublingual/Swallow Immunotherapy Improves the Quality of Life of Polysensitized Children and Adults with Allergic Rhinitis

Abstract

Citation: Olivier CE, dos Santos Lima RP, Argentão DGP, da Silva MD, dos Santos RAPG, et al. (2013) AbstractBackground: The treatment of polysensitized allergic patients continues to represent a challenge and is a matter for debate amongst allergists who preferentially use allergen-specific immunotherapy.Objective: To study the effect of group-specific sublingual/swallow immunotherapy on quality of life of polysensitized human subjects with allergic rhinitis diagnosed using a comprehensive panel of cutaneous tests.Methods: 60 polysensitized subjects diagnosed with allergic rhinitis who submitted to group-specific sublingual/ swallow immunotherapy treatment corresponding to their cutaneous sensitizations, and who completed 6 months of treatment without the use of any complementary medication were evaluated with a validated quality of life questionnaire.Results: There were significant improvements in all quality of life categories evaluated, which included: sleep, systemic symptoms, practical problems, nasal symptoms, eye symptoms, activities and emotions. Conclusions:The administration of a group-specific multi-allergen sublingual/swallow immunotherapy as indicated by a comprehensive panel of sensitizing agents in cutaneous tests performed by a specialized team, significantly improved the quality of life of human polysensitized subjects with allergic rhinitis without the use of any additional medication.

Quality of Life in the Management of Anaphylaxis in Food-Allergic Adults

“…These elements collectively play a vital role in ensuring not only the safety of the patient but also in maintaining their overall quality of life. 3 , 6 , 9 , 10 , 19 The results of the present study further validate this, indicating that FA individuals who strictly adhere to an allergen avoidance regimen significantly reduce their likelihood of anaphylaxis compared to those who do not. However, avoiding certain foods due to allergies may lead to inadequate nutrient intake, potentially resulting in nutritional deficiencies.…”

“…This training and the emergence of food allergen-specific therapies, including oral, sublingual, and epicutaneous immunotherapies, offer hope for a better quality of life for FA patients. 3 , 6 , 9 , 10 Addressing these aspects will ensure the FA patient’s safety and help maintain their overall QoL. 3 …”