Growing epidemic of Human papilloma virus associated malignant and premalignant lesions - A dental surgeon’s perspective

Abstract

Objectives: To explore unique characteristics of HPV related oral malignant and premalignant lesions and to describe role of dental surgeons in prevention of this viral-induced carcinogenesis. Methods: Extensive literature search was conducted to identify articles detailing HPV associated diseases. Data collected were categorised under relevant titles of clinical interest. Results: Peculiarities of HPV linked cancers in head and neck include its different mode of transmission, younger age distribution, irrelevant habit history, good treatment response, better survival rates, less chance of local recurrence and low distant metastasis. Conclusions: The most distinguishing feature of HPV related head and neck cancers is that it is vaccine preventable. Dental surgeons have got an influential role in creating patient awareness regarding this emerging epidemic. The article advocate further research in this regard. Key Message: The carcinogenic potential of Human papilloma virus has been an interesting topic of research for the past few decades. This article discusses the recent epidemiologic and etiologic trends in Human Papilloma Virusassociated head and neck cancers, its presence in precancerous lesions and its implication in dental practise.