Grown-up congenital heart disease: The problem of late arrhythmia and ventricular dysfunction

Capelli, Horacio

doi:10.1016/j.ppedcard.2006.07.005

Cited by 5 publications

(4 citation statements)

References 144 publications

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“…Currently, 5.7 million Americans are estimated to have heart failure, and up to 30% of people who have heart failure die within 1 year from diagnosis . As more children with congenital heart disease are surviving into adulthood, the prevalence of heart failure in this group is increasing . The data regarding outcomes of heart failure–related admissions in adults with congenital heart disease (ACHD) are very limited.…”

Section: Introductionmentioning

confidence: 99%

“…4,5 As more children with congenital heart disease are surviving into adulthood, the prevalence of heart failure in this group is increasing. 6,7 The data regarding outcomes of heart failure-related admissions in adults with congenital heart disease (ACHD) are very limited. We aimed to test the hypothesis that heart failure is common among ACHD and associated with increased morbidity and mortality.…”

Section: Introductionmentioning

confidence: 99%

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Outcomes of Heart Failure-Related Hospitalization in Adults with Congenital Heart Disease in the United States

Rodriguez

Moodie

Parekh

et al. 2012

Congenital Heart Disease

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Outcomes of Heart Failure-Related Hospitalization in Adults with Congenital Heart Disease in the United States

Rodriguez

Moodie

Parekh

et al. 2012

Congenital Heart Disease

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“…As the population of adults with CHD grows, a corresponding increase in the prevalence of arrhythmias is expected, especially pronounced among adults with more severe types of CHD [4]. Late survivors of tetralogy of Fallot, the Fontan operation, and ccTGA showed a close relationship between residual or late-acquired structural abnormalities and the onset of ventricular dysfunction and arrhythmias [15].…”

Section: Discussionmentioning

confidence: 99%

Identifying Arrhythmias in Adults With Congenital Heart Disease by 24-h Ambulatory Electrocardiography

et al. 2012

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Adults with congenital heart disease (CHD) are at risk for the development of arrhythmias. This study aimed to assess the incidence of unsuspected arrhythmias among adults with CHD identified on electrocardiograms (ECGs) and 24-h ambulatory electrocardiographic monitoring (Holter monitoring). A review of the cardiology database at the authors' institution from July 2004 through December 2007 identified all clinic patients 18 years old or older who had a recent ECG and Holter monitoring. Data collection included diagnosis, ECG and Holter monitoring results, arrhythmias, and the presence or absence of symptoms. The review identified 140 patients. Analysis of the ECGs showed that 15% of the patients had an arrhythmia. These arrhythmias consisted of ectopy (6%), supraventricular tachycardia (SVT) (3%), pacemaker issues (2%), and previously unrecognized atrioventricular block (AVB) (1%). The majority of the patients with arrhythmias were asymptomatic (76%). Analysis of the Holter monitoring results showed that 31% of the patients had arrhythmias consisting of ectopy (17%), SVT (12%), ventricular tachycardia (7%), high-grade AVB (5%), and pacemaker issues (3%). Of the patients with arrhythmias, 80% were asymptomatic. Among the patients without arrhythmias on ECG, 26% had arrhythmias noted on Holter monitoring. Of the patients with multiple Holter monitorings performed, 34% had a new arrhythmia noted on repeat monitoring. In conclusion, arrhythmias were present in a significant number of adults with CHD, but the majority were asymptomatic. Among adults with CHD, even those with normal ECGs, arrhythmias were frequently detected on Holter monitoring. In addition, repeat Holter monitoring may identify significant arrhythmias over time.

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“…Other remaining challenges for Latin America include the following: improving the development of prenatal diagnosis, organizing effective follow-up after surgery, and creating specialized centers to deal with the increasing community and new problems of adult congenital heart disease, particularly with their surgical treatment. 33 Finally, we must also devote time and effort to the development of research in basic sciences.…”

Section: Future Prospectsmentioning

confidence: 99%

Development of Pediatric Cardiology in Latin America

Capelli

Kreutzer

2010

World J Pediatr Congenit Heart Surg

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Until the first quarter of the 20th century, most physicians were more than happy to differentiate congenital heart lesions from rheumatic heart disease, which then was rampant. As early as 1932, Dr Rodolfo Kreutzer, from Buenos Aires, Argentina, was already involved in the study of congenital heart defects. He started off assessing children with a stethoscope and with Einthoven electrocardiography equipment. The cardiac unit at the Buenos Aires Children's Hospital was created in 1936. It established the onset of pediatric cardiology in Argentina and fueled its development in South America. Nearly at the same time, Agustin Castellanos from Cuba also became a pioneer in the assessment of congenital heart disease. He described the clinical applications of intravenous angiocardiography in 1937. Meanwhile in Mexico, Dr Ignacio Chavez founded the National Institute of Cardiology in 1944 in Mexico City. It was the first center in the world to be exclusively devoted to cardiology. From this center, Victor Rubio and Hugo Limon performed the first therapeutic cardiac catheterization in 1953. Meanwhile, Professor Euriclydes Zerbini from Sao Paulo, Brazil, built the largest and most important school of cardiac surgeons in South America. In Santiago, Chile, the Calvo Makenna Hospital was the center where Helmut Jaegger operated on the first infant with extracorporeal circulation in Latin America in 1956. The patient was a 1-month-old baby, with complete transposition of the great arteries, who underwent an Albert procedure. Currently, there are many fully equipped centers all over the region, capable of dealing with most lesions and of providing excellent medical, interventional, and surgical treatment. Outcomes have improved substantially over the last 20 years. These achievements have gone beyond our pioneers' dreams. However, many neonates and young infants die prior to surgery because referral centers are overburdened and have long surgical waiting lists. Clearly, we still have to mastermind and establish sustainable public health policies to overcome these challenges.

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Grown-up congenital heart disease: The problem of late arrhythmia and ventricular dysfunction

Cited by 5 publications

References 144 publications

Outcomes of Heart Failure-Related Hospitalization in Adults with Congenital Heart Disease in the United States

Outcomes of Heart Failure-Related Hospitalization in Adults with Congenital Heart Disease in the United States

Identifying Arrhythmias in Adults With Congenital Heart Disease by 24-h Ambulatory Electrocardiography

Development of Pediatric Cardiology in Latin America

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