Growth After Neonatal Small Bowel Resection

Baglin-Gobet, S.; Jais, J.P.; Dabbas, M.; Colomb, V.; Jan, D.; Jobert-Giraud, A.; Révillon, Y; Ricour, C; Goulet, Olivier

doi:10.1097/00005176-199905000-00192

Cited by 4 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Long term nutritional status and growth must be monitored carefully (56)(57)(58). Most children show a normal growth pattern, experience normal puber-tal development and achieve a normal adult size (58). However, some children may experience growth failure after PN weaning and require resumption of IV nutritional support, especially during puberty (58).…”

Section: Outcome and Delay In Weaning From Parenteral Nutritionmentioning

confidence: 99%

“…Most children show a normal growth pattern, experience normal puber-tal development and achieve a normal adult size (58). However, some children may experience growth failure after PN weaning and require resumption of IV nutritional support, especially during puberty (58). In patients with ileal resection, the risk of fat soluble vitamin deficiency, vitamin B12 deficiency and cholelithiasis are markedly increased.…”

Section: Outcome and Delay In Weaning From Parenteral Nutritionmentioning

confidence: 99%

“…However, even when complete oral feeding can be achieved, there may be dietary restrictions and some degree of residual malabsorption. Long term nutritional status and growth must be monitored carefully (56)(57)(58). Most children show a normal growth pattern, experience normal puber-tal development and achieve a normal adult size (58).…”

Section: Outcome and Delay In Weaning From Parenteral Nutritionmentioning

confidence: 99%

See 2 more Smart Citations

Irreversible Intestinal Failure

Goulet,

Ruemmele,

Lacaille

et al. 2004

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

Intestinal failure (IF) can be defined as the reduction of functional gut mass below the minimal amount necessary for digestion and absorption adequate to satisfy the nutrient and fluid requirements for maintenance in adults or growth in children. In developed countries, IF mainly includes individuals with the congenital or early onset of conditions requiring protracted or indefinite parenteral nutrition (PN). Short bowel syndrome was the first commonly recognized cause of protracted IF. The normal physiologic process of intestinal adaptation after extensive resection usually allows for recovery of sufficient intestinal function within weeks to months. During this time, patients can be sustained on parenteral nutrition. Only a few children have permanent intestinal insufficiency and life‐long dependency on PN. Non‐transplant surgery including small bowel tapering and lengthening may allow weaning from PN in some cases. Hormonal therapy with recombinant human growth hormone has produced poor results while therapy with glucagon‐like peptide‐2 holds promise. Congenital diseases of enterocyte development such as microvillus inclusion disease or intestinal epithelial dysplasia cause permanent IF for which no curative medical treatment is currently available. Severe and extensive motility disorders such as total or subtotal intestinal aganglionosis (long segment Hirschsprung disease) or chronic intestinal pseudo‐obstruction syndrome may also cause permanent IF. PN and home‐PN remain are the mainstays of therapy regardless of the cause of IF. Some patients develop complications while receiving long‐term PN for IF especially catheter related complications (thrombosis, sepsis) and liver disease. These patients may be candidates for intestinal transplantation. This review discusses the causes of irreversible IF and emphasizes the specific medico‐surgical strategies for prevention and treatment of these conditions at several stages of IF.

show abstract