Growth and behavior of epidermis as observed microscopically in observation chambers inserted in the ears of rabbits

Fibrinolytic activity of human oral epithelial cells

“…The implications of the findings of the present study are difficult to evaluate, but as injury seems to be a necessary factor in the liberation of the plasminogen activators, interest concmtrates on the role of fibrinolysis in wound healing. Thr: present study brings support to the theory that epithelia1 fibrinolysis is a possible factor in the dissolution of fibrin during epithelial migration in wound healing (CLARK & CLARK 1953, G I L L M A N & PENN 1956, WINTER 1964.…”

Molecular Adhesion between Cartilage Extracellular Matrix Macromolecules

“…35 For the trypsin-only treated collagen network, the fibril diameter was found to be 40.5 ± 4.7 nm (mean ± STD, n ≥ 100 fibrils), with a packing density of ≈50 fibrils per μm 2 area (Figure 6). At this length scale, effects of either MMP-13 or bacterial collagenase treatments were not noticeable (Figure 6a,b).…”

Plastic Surgery: Homotransplantation, Congenital Anomalies, Wound Healing, and Skin Storage

“…The earliest microscopic evidence of wound activity is in the epidermis which rapidly migrates across the wound either through or beneath the intervening clot. A fibrinolytic enzyme or other proteolytic enzyme is presumed to be formed by the epithelium enabling it to advance beneath the clot (39). Active cell mitosis appears at a distance from the incision and the thickened epidermis grows downward between the edges of the incision and also follows the path of each skin suture.…”