Growth and Concentration of Serum Insulin-like Growth Factor-1 in Japanese Black Cattle with Growth Retardation

Alterations of Growth, Blood Biochemical Components and Hormone Profiles by Intensified Nutrition in Growth Retarded Japanese Black Cattle

“…Increased nutritional supply increases the serum IGF-1 concentration, and then it decreases serum GH [3,4,6]. Regarding the former reports of GH and IGF-1 in growth retarded JB cattle [9,19,20,22] and retarded Brahman cattle [5], the serum GH concentra- tions and amplitude of GH pulses increased with low concentrations of serum IGF-1. Our study showed similar results during the Pre period in addition to low concentrations of serum Alb, TC and T4 and plasma glucose.…”

“…However, many cattle with normal appetite and activities are also categorized as growth retarded [7-10, 13, 19-22, 24, 27]. Kitagawa et al [8,9] and Takasu et al [19][20][21][22]24] investigated JB cattle with retarded growth and suggested that they had an abnormal IGF-1-GH axis that exhibits higher GH and lower IGF-1 concentrations. These retarded cattle also had abnormalities of energy and protein metabolism that were verified by their blood profiles.…”

“…Thus, retarded growth cattle with a normal appetite might arise from various factors. Longitudinal study of growthretarded cattle has been sparse [20], and the physiological mechanism and clinical condition of growth retardation remain to be elucidated. The purpose of this study was to clarify the cause and physiological mechanism of growth retardation by investigating the changes of body weight (BW), height, daily gain (DG), blood concentrations of growth related hormones and metabolic profiles following a diet with intensified protein and energy.…”

Sugar Supplementation Stimulates Growth Performance in Calves with Growth Retardation

“…The growth effect of sugar supplementation could be stimulated through rumen papillae development induce by sucrose, the main component of A variety of studies have been performed on retarded growth calves in respect to endocrinology, i.e., blood profiles of growth hormone (GH), insulin-like growth factor-1 (IGF-1) [2,3,6,8,15] and thyrotropin [3,4,12], but most of these studies have focused on the pathophysiological aspects, and therefore, the results have been rather difficult to apply directly to field conditions. Recently, nutritional aspects along with an organic physiology have been determined based on production medicine [9][10][11]14] under the concept of a safe table food supply. Calves that seem clinically healthy but exhibit retarded growth become major factors that deteriorate the efficiency and profitability of beef farm enterprises.…”

“…Recently, nutritional aspects along with an organic physiology have been determined based on production medicine [9][10][11]14] under the concept of a safe table food supply. Calves that seem clinically healthy but exhibit retarded growth become major factors that deteriorate the efficiency and profitability of beef farm enterprises.…”