Growth and metabolic responses to methyl viologen (1,1′-dimethyl - 4,4′-bipyridinium dichloride) on Chlorella vulgaris

Perales-Vela, Hugo Virgilio; Salcedo-Álvarez, Martha Ofelia; Parra-Marcelo, Rogelio; Gaviria-González, Llaraí Carolina; Martínez-Roldán, Alfredo de Jesús

doi:10.1016/j.chemosphere.2021.130750

Cited by 11 publications

(2 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most recognized and largely produced algae xanthophylls are lutein, astaxanthin, canthaxanthin, and fucoxanthin [ 17 ]. Although these pigments are produced during the vegetative phase, as they are responsible for light-harvesting, it is known that their production can be influenced by various biotic and abiotic factors such as light intensity and duration, nutrient availability, pH, temperature, salinity, and heavy metals [ 27 , 28 , 29 , 30 ].…”

Section: Discussionmentioning

confidence: 99%

Xanthophyll-Rich Extract of Phaeodactylum tricornutum Bohlin as New Photoprotective Cosmeceutical Agent: Safety and Efficacy Assessment on In Vitro Reconstructed Human Epidermis Model

Smeriglio,

Lionti,

Ingegneri

et al. 2023

Molecules

View full text Add to dashboard Cite

The nutritional and health properties of algae make them perfect functional ingredients for nutraceutical and cosmeceutical applications. In this study, the Phaeodactylum tricornutum Bohlin (Phaeodactylaceae), a pleiomorphic diatom commonly found in marine ecosystems, was investigated. The in vitro culture conditions used favoured the fusiform morphotype, characterized by a high accumulation of neutral lipids, as detected by fluorescence microscopy after BODIPY staining. These data were confirmed by HPLC-DAD-APCI-MS/MS analyses carried out on the ethanolic extract (PTE), which showed a high content of xanthophylls (98.99%), and in particular of fucoxanthin (Fx, 6.67 g/100 g PTE). The antioxidant activity (ORAC, FRAP, TEAC and β-carotene bleaching) and photostability of PTE and Fx against UVA and UVB rays were firstly evaluated by in vitro cell-free assays. After this, phototoxicity and photoprotective studies were carried out on in vitro reconstructed human epidermidis models. Results demonstrated that PTE (0.1% Fx) and 0.1% Fx, both photostable, significantly (p < 0.05) reduce oxidative and inflammatory stress markers (ROS, NO and IL-1α), as well as cytotoxicity and sunburn cells induced by UVA and UVB doses simulating the solar radiation, with an excellent safety profile. However, PTE proved to be more effective than Fx, suggesting its effective and safe use in broad-spectrum sunscreens.

show abstract

Section: Discussionmentioning

confidence: 99%

Xanthophyll-Rich Extract of Phaeodactylum tricornutum Bohlin as New Photoprotective Cosmeceutical Agent: Safety and Efficacy Assessment on In Vitro Reconstructed Human Epidermis Model

Smeriglio,

Lionti,

Ingegneri

et al. 2023

Molecules

View full text Add to dashboard Cite

show abstract

“…Paraquat (PQ) and diquat (DQ) are representative high-water-solubility herbicides with a bipyridinium structure. When they enter the plant body, reactive oxygen species harmful to the growth of the plant are produced, inhibiting the photosynthetic activity and affecting many other metabolic reactions; 1,2 they are also fast-acting and non-selective. Because of their usefulness, these herbicides have been produced by many companies and are widely used around the world.…”

Section: Introductionmentioning

confidence: 99%