Growth, characterisation and applications of L lysine zinc sulphate crystals

Abstract

L lysine zinc sulphate single crystals were developed by solution growth slow evaporation method at ambient temperature using deionised water solvent. Single and powder XRD confirmed the crystalline nature and the lattice parameters identified that the grown crystal crystallised in monoclinic crystal system with the space group of C 2/c. FTIR analysis substantiated the findings of XRD. Optical analysis proved that the grown crystal had wide transparency window (78%) with the lower cut off value 230 nm and its band gap energy was 5.3 eV. High dielectric constant and high dielectric loss at low frequency and vice versa guaranteed their applications. When assayed against select bacterial strains and in vitro human cervical cancer cell line (HeLa), the grown crystal established its efficiency as potential pharmaceutical drug. It showed 100% cancer cell inhibition at very low sample concentration of 50 μg/ml with the IC 50 value of 28.84 μg/ml.

A Study Of Growth And Characteristics Of Metal Salt Like Manganese Sulphate [MnSO4] Doped In L Threonine Amino Acid Single Crystal For NLO Application

“…Examples of NLO materials are Barium borate, cadmium lithium borate, lithium iodate, Monopotassium phosphate, zinc oxide, Tellurium dioxide [39]. These NLO Crystals are further categories to Inorganic NLO -eg KCL, lithium niobate (LiNbO3) or potassium dihydrogen phosphate (KH2PO4) , KDP , (KTiOPO4), Barium metaborate, Methyl parahydroxyl benzoate e.t.c [40], [41].Organic NLO crystal -4-dimethylamino-N-methyl-4-stilbazolium-tosylate(DAST),2-(3-(4hydroxystyryl)-5,5-dimethylcyclohex-2enylidene)malononitrile OH1) [42].Semi organic NLO crystal -BTCC: Bis(thiourea) cadmium chloride, Bis-thiourea cobalt chloride (BTCoC),ATCC triallyl thiourea cadmium chloride, ATMB Triallyl thiourea mercury bromide,TSCCB thiosemicarbazide cadmium bromide, zinc thiourea chloride (ZTC) , 4-aminophenyl)sulphonyl)oxy)zinc(II)chloride Crystal [43], [44], [45], [46], [47] [48], Various techniques like solvent evaporation, slow cooling of the solution, solvent/ non-solvent diffusion, vapor diffusion and sublimation for crystals formation of NLO materials [1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [25], [26], [27], [30], [31], [32], [33].Due to chiral carbon atom and no centrosymmetric space group, an Amino acid crystal has excellent NLO and electro optical properties. Biosynthesis pathway in bacteria & plants categorizes Amino Acid to six families as Histidine, Aromatic, pyruvate, serine, aspartate, glutamate family respectively [49].…”

“…Nonlinear optics play a major role in many of the optical applications such as optical signal processing, optical computers, ultrafast switches, ultra-short pulsed lasers, sensors, laser amplifiers, and many others. In many research work , it was prominently seen that traditional slow evaporation technique at room temperature with water as the solvent was adopted for crystals formation like L Threonine on zinc acetate LTZA [1], [2] bis( Lthreonine)zinc(II) (BLTZ) [3], L-threonine phosphate (LTP) [4] ,L-threonine doped ADP crystals [5], DLmethionine doped ADP crystal [6] L-methionine L-methionine hydrogen maleate (LMMM) [7], dl-methionine hydrochloride [8], L-asparagine monohydrate (LAM) [9], [10],Ammonium Dihydrogen Orthophosphate (ADP) doped with L-Asparagine (LAADP) [11],urea L-asparagine [12] L lysine zinc sulphate [13] were grown successfully. It was also observed in research work that apart from water as solvent, ethyl acetate and hexane also can be used as solvent to grow L-isoleucine with triphosgeen [14] Research work done by S. Kalainathan on crystals of L-threonine to determine band gap for all the crystals of L-threonine at different pH 4.40, 5.87 and 6.80.…”