Growth Control of Metal–Organic Framework Films on Marine Biological Carbon and Their Potential-Dependent Dopamine Sensing

Abstract

Ever-evolving advancements in films have fueled many of the developments in the field of electrochemical sensors. For biosensor application platforms, the fabrication of metal–organic framework (MOF) films on microscopically structured substrates is of tremendous importance. However, fabrication of MOF film-based electrodes always exhibits unsatisfactory performance, and the mechanisms of the fabrication and sensing application of the corresponding composites also need to be explored. Here, we report the fabrication of conformal MIL-53 (Fe) films on carbonized natural seaweed with the assistance of an oxide nanomembrane and a potential-dependent electrochemical dopamine (DA) sensor. The geometry and structure of the composite can be conveniently tuned by the experimental parameters, while the sensing performance is significantly influenced by the applied potential. The obtained sensor demonstrates ultrahigh sensitivity, a wide linear range, a low limit of detection, and a good distinction between DA and ascorbic acid at an optimized potential of 0.3 V. The underneath mechanism is investigated in detail with the help of theoretical calculations. This work bridges the natural material and MOF films and is promising for future biosensing applications.

Fabrication of NiCo Bimetallic MOF Films on 3D Foam with Assistance of Atomic Layer Deposition for Non-Invasive Lactic Acid Sensing

“…The characterizations of other composites are summarized in Figure S23 and the increasing trend is similar to that of the Ni 1 Co 5 BMOF@Ni foam. In this work, the active area ( S ) of detection electrode is calculated according to the Randles–Sevcik formula: where n is the amount of transferred electrons, D and C are the diffusion coefficient and bulk concentration of K 3 [Fe­(CN) 6 ], respectively. Therefore, a series of S are evaluated to be 0.23, 0.25, 0.29, 0.37, and 0.28 cm 2 for the produced composite electrodes according to the slope of peaks response current and the square root of scanning rate (Figure f).…”

“…31,32 As illustrated in our previous works, there was an efficient strategy developed for integrating MOF films into complex conductive substrates via induction of oxide nanomembrane prepared by atomic layer deposition (ALD). 33 ALD technology enables the deposition of uniform and conformal metal oxide nanomembranes with controlled thickness on a variety of substrates, including silicon wafers, carbon materials, and polymers., 34−36 Thanks to gaseous deposition, metal oxide nanomembranes can be uniformly grown on the complex 3D structures. 37 By using the following hydrothermal reaction, the oxide nanomembrane could be transformed into the target MOF film, which can uniformly and firmly attach to the substrates.…”

“…Moreover, the planar electrode structure cannot provide sufficient surface area for ion diffusion and interaction, reducing signal transmission capacity. − In order to improve the performance of the electrode, fabrication of 3D structure/BMOFs composite is explored . Although advantageous devices have been preliminary demonstrated, there are still many problems that need to be addressed, such as weak adhesion and ununiform growth. , As illustrated in our previous works, there was an efficient strategy developed for integrating MOF films into complex conductive substrates via induction of oxide nanomembrane prepared by atomic layer deposition (ALD) . ALD technology enables the deposition of uniform and conformal metal oxide nanomembranes with controlled thickness on a variety of substrates, including silicon wafers, carbon materials, and polymers., − Thanks to gaseous deposition, metal oxide nanomembranes can be uniformly grown on the complex 3D structures .…”

Detection of epinephrine using a K2Fe4O7 modified glassy carbon electrode

“…Consequently, ironcontaining materials have shown promise in biosensor applications. Recent studies have successfully detected dopamine (DA), another catecholamine neurotransmitter, using electrodes modied with iron oxide nanoparticles, [16][17][18] Fe-based metal-organic frameworks (MOFs), 19 and cobalt-doped FePS 3 . 20 However, no reported electrode is modied by ironbased materials that demonstrate electrocatalytic activity for the oxidation of EP.…”

Paper Sensor Modified with MoS2 for Detection of Dopamine Using a Machine-Intelligent Web App Interface

“…Thus, in recent years, research has shifted toward the development of simple, low-cost point-of-care diagnostic devices that can provide an immediate response to the user in the hour of need. The electrochemical biosensors fulfill these criteria and have become a standard option in the scientific community due to their low cost, high sensitivity, good specificity, low response time, and compatibility with integrated circuit technology for easy readout. − Herein, DA being an easily oxidized electroactive molecule and having an oxidation potential in the potential window of several electrodes, the electrochemical method is presumed to be an innate choice for DA detection. − …”