1994
DOI: 10.1016/s0074-7696(08)62096-3
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Growth Factor-Induced Cell Migration: Biology and Methods of Analysis

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Cited by 40 publications
(25 citation statements)
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“…More recently, FGF4 and FGF8 have been shown to control directional movement of streak cells in the chick (Yang et al, 2002). These data demonstrate that FGFs are able to control both gene expression and cellular behaviour (for reviews, see Manske and Bade, 1994;Montell, 1999;Boilly et al, 2000) and they raise the possibility that during mesoderm development, Ras not only mediates the induction of gene expression by FGF signalling, but also controls the cellular behaviour.…”
mentioning
confidence: 89%
“…More recently, FGF4 and FGF8 have been shown to control directional movement of streak cells in the chick (Yang et al, 2002). These data demonstrate that FGFs are able to control both gene expression and cellular behaviour (for reviews, see Manske and Bade, 1994;Montell, 1999;Boilly et al, 2000) and they raise the possibility that during mesoderm development, Ras not only mediates the induction of gene expression by FGF signalling, but also controls the cellular behaviour.…”
mentioning
confidence: 89%
“…EGF-dependent cell motility is regulated by phospholipase c-a activation [222,223] and MAPK activation [224]. EGF can stimulate the disassembly of focal adhesions and alter components of the adherens [225] and desmosomal junctions, thus decreasing cell-cell contact and contributing to cell motility [226]. Therefore, TGF-b and EGF can have opposing roles in terms of proliferation, but similar roles in terms of migration.…”
Section: Functions Of Egfr Ligandsmentioning
confidence: 99%
“…in tissue culture represents in many aspects a model system of the epithelial-mesenchymal transition (38). We chose for our studies the rat bladder carcinoma cell line NBT II (39) because certain growth factors and components of the extracellular matrix induce migration of these cells (40 -42).…”
Section: Relocalization Of the Cadherin-catenin Complex Upon Inductiomentioning
confidence: 99%