Growth Factors in Periodontal Regeneration

Abstract

The disintegration of the periodontal ligament, the root cementum and the alveolar bone is the result of periodontal disease, which is caused by bacteria found in dental plaque. The ultimate objective of periodontal therapy is the regeneration of the attachment apparatus. Numerous growth and differentiation variables in periodontal regeneration have been evaluated. The primary regulators of these biological processes are a class of naturally occurring chemicals known as polypeptide growth factors in combination with certain matrix proteins. Four main growth factors that seem to have a considerable impact on the process of wound healing will be covered in this review article. Bone morphogenetic proteins, fibroblast growth factors, transforming growth factor, and platelet-derived growth factor.