Growth hormone-responsive alopecia in dogs

Frank, Linda A.

doi:10.2460/javma.2005.226.1494

Cited by 23 publications

(21 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…See the comprehensive review of Frank (2005) and the section on hair cycle arrest in the latest edition of Muller and Kirk's Small Animal Dermatology (Miller et al, 2013) for more details, as well as the previous edition of this textbook for the references of the multiple studies performed on this topic. They are not always effective, and because hair cycle arrest is a "cosmetic" disease, the risk of treatment has to weigh against the benefit.…”

Section: Dogs and Catsmentioning

confidence: 99%

Disorders of Growth Hormone

Reusch¹

2015

Canine and Feline Endocrinology

View full text Add to dashboard Cite

Section: Dogs and Catsmentioning

confidence: 99%

Disorders of Growth Hormone

Reusch¹

2015

Canine and Feline Endocrinology

View full text Add to dashboard Cite

“…Dogs with hyperadrenocorticism have decreased response of GH after stimulation with xylazine, clonidine, and growth hormone-releasing hormone (GHRH) (Frank, 2005). Dogs with hyperadrenocorticism have decreased response of GH after stimulation with xylazine, clonidine, and growth hormone-releasing hormone (GHRH) (Frank, 2005).…”

Section: Growth Hormone and Gonadotropinsmentioning

confidence: 99%

Glucocorticoid Therapy

Reusch¹

2015

Canine and Feline Endocrinology

View full text Add to dashboard Cite

“…Although some alopecic disorders are inflammatory in nature, the most problematic cases are often noninflammatory with a symmetrical appearance. Diseases routinely associated with noninflammatory symmetrical alopecia include endocrinopathies such as hypothyroidism, hyperadrenocorticism, sex hormone imbalances and a frequently renamed syndrome currently referred to as Alopecia X . Alopecia X typically affects double‐haired “plush‐coated” breeds such as the chow chow, Pomeranian and Alaskan malamute; the miniature poodle also has been reported as a commonly affected breed .…”

Section: Introductionmentioning

confidence: 99%

Description and characterization of a hair coat disorder in schipperkes

May

Frank

Sula

2018

Veterinary Dermatology

Self Cite

View full text Add to dashboard Cite

Background Schipperkes develop bilaterally symmetrical alopecia preceded by lightening of the hair coat not associated with systemic clinical signs. The alopecia is presumptively diagnosed as Alopecia X but has never been investigated. Hypothesis/Objectives The purpose of this study was to describe clinical features, histopathological and laboratory abnormalities associated with symmetrical, noninflammatory alopecia in schipperkes. Animals Three healthy and eight affected schipperkes. Methods and materials Complete blood count (CBC), serum chemistry panel, urinalysis (UA), urine cortisol: creatinine ratio (UCCR), total thyroxine (T4), free thyroxine by equilibrium dialysis (fT4ed), thyroid stimulating hormone (TSH) and pre‐ and post‐stimulation cortisol with sex hormone analyses were performed for all dogs. A minimum of two skin biopsy sites were sampled for histopathological evaluation. Results The CBC, serum chemistry panel, UA, T4, fT4ed, TSH and post‐ACTH cortisol concentrations were normal for all dogs. Androstenedione concentrations were increased for all dogs; two of three healthy and five of eight affected dogs had increased post‐ACTH androstenedione concentrations. Estradiol concentrations were increased for all healthy and four of eight affected dogs, with post‐ACTH estradiol concentrations increased for all healthy and five of eight affected dogs. Progesterone concentrations were increased for two of three healthy and four of eight affected dogs. Post‐ACTH progesterone concentrations were increased for one of three healthy and four of eight affected dogs. For one of three healthy and two of eight affected dogs, 17‐hydroxyprogesterone concentrations were increased; post‐ACTH 17‐hydroxyprogesterone concentrations were increased in three of eight affected dogs only. Histopathology results from affected dogs were consistent with hair cycle arrest. Conclusions and clinical importance This disorder resembles Alopecia X clinically and histologically.

show abstract

Growth hormone-responsive alopecia in dogs

Cited by 23 publications

References 30 publications

Disorders of Growth Hormone

Disorders of Growth Hormone

Glucocorticoid Therapy

Description and characterization of a hair coat disorder in schipperkes

Contact Info

Product

Resources

About