Growth inhibition of harmful cyanobacteria by nanocrystalline Cu-MOF-74: Efficiency and its mechanisms

Fan, Gongduan; Bao, Minchen; Zheng, Xiaomei; Liang, Hong; Zhan, Jiajun; Chen, Zhong; Qu, Fangshu

doi:10.1016/j.jhazmat.2018.12.070

Cited by 80 publications

(23 citation statements)

References 39 publications

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“…The relative stable frame structure of zinc base MOF makes it possible to degrade slowly in aqueous environment. With the slow degradation of MOF materials, the long-term release of metal ions can be achieved [ 15 , 36 ], which greatly reduces the toxicity of metal ions and prolongs the function time.…”

Section: Introductionmentioning

confidence: 99%

Zinc-based metal organic framework with antibacterial and anti-inflammatory properties for promoting wound healing

Chen

Cai

Liu

et al. 2022

Regenerative Biomaterials

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The synergistic effect of antibacterial and anti- inflammatory is needed to overcome the problem of wound healing difficulties. Based on the favorable antibacterial and anti- inflammatory effect of zinc ions (Zn2+) and the physicochemical properties of metal organic frameworks (MOFs), we prepared nanosized zinc-based MOF: Zn-BTC with the ability to slowly release Zn2+. In cellular levels, Zn-BTC possessed lower toxicity to fibroblasts and enhanced capacity of cell proliferation and migration. It also had good bactericidal effect on multiple drug resistant (MDR) bacteria by reducing 41.4% MRSA and 47.2% E. coli. In addition, Zn-BTC also displayed the ability of lowering the expression of antioxidant genes: superoxide dismutase 1 (SOD1), superoxide dismutase 2 (SOD2) and interleukin 6 (IL6), and enhancing the expression of wound healing genes: transforming growth factors-β (TGF-β) and type I collagen (COL1). Finally, it also demonstrated that Zn-BTC could effectively improve the skin wound healing of SD rats and had no toxicity on major organs. The favorable biocompatibility, antibacterial and anti- inflammatory properties of Zn-BTC gave a new insight of designing novel MOFs for promoting skin wound healing.

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Section: Introductionmentioning

confidence: 99%

Zinc-based metal organic framework with antibacterial and anti-inflammatory properties for promoting wound healing

Chen

Cai

Liu

et al. 2022

Regenerative Biomaterials

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“…A zinc-containing nanoscale MOF has shown particle-induced cellular effects towards neural cells and demonstrated a time- and concentration-dependent toxicity on rat pheochromocytoma cells [ 20 ]. Preliminary toxicity assessment showed that the presence of metal atoms in MOFs network could influence the homeostasis of the exposed live system both extracellularly and intracellularly [ 21 , 22 ]. According to the research by Tamames-Tabar et al, the cytotoxicity of MOFs NPs depends on the nature of metal ions in their structure, as well as on the tested cell line [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Acute Toxicity of Cu-MOF Nanoparticles (nanoHKUST-1) towards Embryos and Adult Zebrafish

Abramenko

Deyko

Abkhalimov

et al. 2021

IJMS

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Metal-organic frameworks (MOFs) demonstrate unique properties, which are prospective for drug delivery, catalysis, and gas separation, but their biomedical applications might be limited due to their obscure interactions with the environment and humans. It is important to understand their toxic effect on nature before their wide practical application. In this study, HKUST-1 nanoparticles (Cu-nanoMOF, Cu3(btc)2, btc = benzene-1,3,5-tricarboxylate) were synthesized by the microwave (MW)-assisted ionothermal method and characterized by X-ray powder diffraction (XRD) and transmission electron microscopy (TEM) techniques. The embryotoxicity and acute toxicity of HKUST-1 towards embryos and adult zebrafish were investigated. To gain a better understanding of the effects of Cu-MOF particles towards Danio rerio (D. rerio) embryos were exposed to HKUST-1 nanoparticles (NPs) and Cu2+ ions (CuSO4). Cu2+ ions showed a higher toxic effect towards fish compared with Cu-MOF NPs for D. rerio. Both forms of fish were sensitive to the presence of HKUST-1 NPs. Estimated LC50 values were 2.132 mg/L and 1.500 mg/L for zebrafish embryos and adults, respectively. During 96 h of exposure, the release of copper ions in a stock solution and accumulation of copper after 96 h were measured in the internal organs of adult fishes. Uptake examination of the major internal organs did not show any concentration dependency. An increase in the number of copper ions in the test medium was found on the first day of exposure. Toxicity was largely restricted to copper release from HKUST-1 nanomaterials structure into solution.

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“…Accordingly, studies related to the detection of hazardous chemicals present in solutions at low levels could be explored for the detection of various analytes in future. [106] These sensors use different types of the parameter to calculate the detection and sensing results. [107,108]…”

Section: Toxic Chemicals and Their Detectionmentioning

confidence: 99%

Mechanistic Insight into Charge and Energy Transfers of Luminescent Metal–Organic Frameworks Based Sensors for Toxic Chemicals

Mohan

Kumar

et al. 2021

Advanced Sustainable Systems

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The success of MOFs has driven their development as a new tool for sensing analytes including toxic chemicals. [19][20][21] The MOF sensors can be applied in both environmental and biological systems. [22] The MOF sensor field has been established with the development of sensors for different metal ions, anions, and molecules. [23,24] The potential application of MOF sensors to the detection of heavy metal ions, toxic anions, and other hazardous species is of great interest. [25,26] Specifically, luminescence technology has allowed the roles of various MOF sites in analyte capture to be easily studied. [27][28][29] The precise use of MOFs is potentially a good tool for analyte detection. Furthermore, MOFs have been established as potential materials for selective, fast, and portable tools for sensing toxic chemicals, with the advantage of light-emitting properties. [30,31] Interestingly, these sensing models can operate in water and are pH stable with high efficiency. [32] Furthermore, MOFs are wellknown materials for the degradation of toxic chemicals. [33,34] Several reports have been published on MOF sensors for toxicant chemicals, such as metal ions, anions, organic solvents, pesticides, nitroaromatic compounds (NACs), chemical warfare agents, [35] and others. [36][37][38] Some reviews have summarized applications of MOFs in sensing and detection probes for ions and volatile organic compounds, [39] and MOF sensors in pesticide detection and absorption with their classification. [40] Others have summarized and analyzed interactions between hazardous compound adsorbates and MOFs. [41,42] The stability and applications of MOFs have been summarized by the research groups of Ding and coworkers. [43] Pehlivan and et al. summarized the role of fluorescence resonance energy transfer in elucidating molecular interactions utilized in biosensing tools. [44,45] Besides luminescence sensing, the reviewers summarized the progress of MOFs relevance in the various area including environment and medical science. [46] Recently, Liu and coworkers summarized the progress of MOFs and discussed the remaining challenges in drug delivery, [47] Garcia and coworkers studied and compared the MOFs as photocatalysts with common inorganic photocatalysts, [48] and Manos and coworkers studied and summarized MOFs challenges and prospects for ion-exchange and sorption applications. [49] Despite these meaningful reviews, the factors responsible for signal changes, mechanisms, and limits of detection have Mechanistic studies of materials able to detect hazardous and toxic chemicals, such as common organic solvents, pesticides, and nitroaromatic compounds (NACs), are critically important owing to the threat they pose to humans and the environment. Recently, porous luminescent metal-organic frameworks (MOFs) with multifunctional sites, high surface areas, and structural tunability have emerged as sensory devices for the detection of hazardous and toxic chemicals. Herein, recent progress regarding the mechanistic behavior of MOF sensors in the det...

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Growth inhibition of harmful cyanobacteria by nanocrystalline Cu-MOF-74: Efficiency and its mechanisms

Cited by 80 publications

References 39 publications

Zinc-based metal organic framework with antibacterial and anti-inflammatory properties for promoting wound healing

Zinc-based metal organic framework with antibacterial and anti-inflammatory properties for promoting wound healing

Acute Toxicity of Cu-MOF Nanoparticles (nanoHKUST-1) towards Embryos and Adult Zebrafish

Mechanistic Insight into Charge and Energy Transfers of Luminescent Metal–Organic Frameworks Based Sensors for Toxic Chemicals

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