Growth of a solitary pulmonary nodule after 6 years diagnosed as oncocytic carcinoid tumour with a high 18‐fluorodeoxyglucose (18F‐FDG) uptake in positron emission tomography‐computed tomography (PET‐CT)

Abstract

We present a rare case of an oncocytic carcinoid tumour with an increase in the size of a solitary pulmonary nodule after 6years' follow-up. In addition, PET-CT showed a very high 18F-FDG uptake in this patient, which is an unexpected finding with a pulmonary carcinoid tumour.

Dynamic contrast-enhanced MRI versus 18F-FDG PET/CT: Which is better in differentiation between malignant and benign solitary pulmonary nodules?

“…18 F-FDG PET/CT reflects the glucose metabolism of various tissues. Malignant nodules consist of metabolically active cells that have higher levels of glucose uptake due to overexpression of glucose transporter proteins (27,28). 18 F-FDG becomes trapped and accumulates within these cells, as the radiolabeled glucose analogue is phosphorylated once but not metabolized further.…”

Radial EBUS versus CT-guided needle biopsy for evaluation of solitary pulmonary nodules

“…With the wide application of high-resolution spiral CT [ 2 , 3 ], SPNs are detected at an increasing rate [ 4 – 6 ]. Quite a number of them represented malignant and were forthcoming lung cancer in early stage, thus the pathological diagnosis of SPN is urgently needed to comfirm as early as possible [ 7 ]. Although computed tomography guided percutaneous needle biopsy (CT-PNB) has been regarded as an useful tool for SPNs pathological diagonsis with the highest diagnostic accuracy reported as more than 90% [ 8 ], complications such as pneumothorax and pulmonary haemorrhage are relatively high too [ 9 , 10 ].…”

Oncocytic carcinoid tumor of the lung complicated by tuberculosis

“…First reported in 1937, OCTL is a specific type of bronchial carcinoid tumor that accounts for 1% to 2% of all lung malignancies and is characterized by neuroendocrine differentiation. [1] It is derived from the bronchial mucosal Kulchitsky cells, which exhibit eosinophilic cytoplasm due to compensatory hyperplasia of the mitochondria in addition to neurosecretory granules. Mitochondrial lesions are considered the cause of OCTL.…”

“…OCTL is a low-grade malignant lung tumor that is often treated with surgery due to its insensitivity to chemotherapy. [1,5] Among the reported cases treated with surgical resection, no metastasis or death occurred during follow-up. Because the prognosis of controlled TB is good, our patient was advised to receive TB treatment first and then treatment of OCTL once the TB was controlled.…”