Growth of calcium phosphate on poling treated ferroelectric BaTiO3 ceramics

Park, Kyung Hee; Hwang, Kyu–Seog; Song, Jong Eun; Ong, Joo L.; Rawls, H. Ralph

doi:10.1016/s0142-9612(02)00123-0

Cited by 55 publications

(22 citation statements)

References 14 publications

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“…The presence of surface charges on HA bioceramics was shown to have a significant effect on both in vitro and in vivo crystallization of biological apatite [336][337][338][339][340]. Furthermore, a growth of both biomimetic calcium orthophosphates and bones was found to be accelerated on negatively charged surfaces and decelerated at positively charged surfaces [340][341][342][343][344][345][346][347][348][349]. In addition, the electrical polarization of HA bioceramics was found to accelerate a cytoskeleton reorganization of osteoblastlike cells [350][351][352], extend bioactivity [353] and enhance bone ingrowth through the pores of porous HA implants [354].…”

Section: Electrical Propertiesmentioning

confidence: 98%

Medical Application of Calcium Orthophosphate Bioceramics

Dorozhkin¹

2011

BIO

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In the late 1960's, a strong interest was raised in biomedical applications of ceramic materials (named bioceramics a little bit later). Bioceramics was initially used as reasonable alternatives to metals in order to increase their biocompatibility. However, within a short period, it has grown into a diverse class of biomaterials, presently including three essential types: relatively bioinert, bioactive (or surface reactive) and bioresorbable bioceramics. This review is limited to bioceramics prepared from calcium orthophosphates only, which belong to the categories of bioactive and bioresorbable compounds. There have been a number of important advances in this field during the past 30 -40 years. The research was shifted from an initial study on the develop-ment of bioinert bioceramics towards bioactive and bioresorbable bioceramics, and these different types of calcium orthophosphate bioceramics can be tuned through the structural and compositional control. At the turn of the millennium, a new concept of calcium orthophosphate bioceramics has been developed to promote a regeneration of bones. Current biomedical applications of calcium orthophosphate bioceramics include artificial replacements for hips, knees, teeth, tendons and ligaments, as well as repair for periodontal disease, maxillofacial reconstruction, augmenttation and stabilization of the jawbone, spinal fusion and bone fillers after tumor surgery. Potential future applications of calcium orthophosphate bioceramics are demonstrated in drug delivery systems, effective carriers of growth factors, bioactive peptides and/or various types of cells for tissue engineering purposes.

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Section: Electrical Propertiesmentioning

confidence: 98%

Medical Application of Calcium Orthophosphate Bioceramics

Dorozhkin¹

2011

BIO

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“…The presence of surface charges on HA bioceramics was shown to have a significant effect on both in vitro and in vivo crystallization of biological apatite [312,313,314,315,316]. Furthermore, growth of both biomimetic calcium orthophosphates and bones was found to be accelerated on negatively charged surfaces and decelerated on positively charged surfaces [316,317,318,319,320,321,322,323,324,325]. In addition, the electrical polarization of HA bioceramics was found to accelerate a cytoskeleton reorganization of osteoblast-like cells [326,327,328], extend bioactivity [329] and enhance bone ingrowth through the pores of porous HA implants [330].…”

Section: The Major Propertiesmentioning

confidence: 99%

Calcium Orthophosphates as Bioceramics: State of the Art

Dorozhkin¹

2010

JFB

216

112

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In the late 1960s, much interest was raised in regard to biomedical applications of various ceramic materials. A little bit later, such materials were named bioceramics. This review is limited to bioceramics prepared from calcium orthophosphates only, which belong to the categories of bioactive and bioresorbable compounds. There have been a number of important advances in this field during the past 30–40 years. Namely, by structural and compositional control, it became possible to choose whether calcium orthophosphate bioceramics were biologically stable once incorporated within the skeletal structure or whether they were resorbed over time. At the turn of the millennium, a new concept of calcium orthophosphate bioceramics—which is able to promote regeneration of bones—was developed. Presently, calcium orthophosphate bioceramics are available in the form of particulates, blocks, cements, coatings, customized designs for specific applications and as injectable composites in a polymer carrier. Current biomedical applications include artificial replacements for hips, knees, teeth, tendons and ligaments, as well as repair for periodontal disease, maxillofacial reconstruction, augmentation and stabilization of the jawbone, spinal fusion and bone fillers after tumor surgery. Exploratory studies demonstrate potential applications of calcium orthophosphate bioceramics as scaffolds, drug delivery systems, as well as carriers of growth factors, bioactive peptides and/or various types of cells for tissue engineering purposes.

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“…In this perspective, BaTiO 3 (BT), a piezoelectric material, seems to be potential biomaterial as it can enhance the bone formation in complex physiological environment [7,8]. BT containing composite (PVDF-TrFE/BT) has also been found as in vivo biocompatible material after testing in rabbit tibiae [9].…”

Section: Introductionmentioning

confidence: 99%

Dielectric and Pyroelectric Properties of HAp-BaTiO₃Composites

et al. 2011

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In order to mimic the electrical properties of natural bone, the present work investigated the dielectric, AC conductivity, pyroelectric and piezoelectric properties of HA-40 wt% BaTiO 3 (HA-26 vol% BaTiO 3 ) and HA-60 wt% BaTiO 3 (HA-44 vol% BaTiO 3 ) composites. Multistage spark plasma sintering was used to achieve the desired combination of properties. The electrical parameters were measured as a function of temperature and frequency. The values of dielectric constant and loss for both the developed composites, measured at room temperature and at 1 KHz frequency was 21, 38 and 0.01 and 0.02, respectively. The AC conductivity for both the composites is found to be of the order of 10 −10 and 10 −9 ( cm) −1 , measured under similar conditions. Activation energy calculated from σ ac vs. temperature plot for HA-40 wt% BaTiO 3 is 0.50 eV. The room temperature pyroelectric coefficients for both the compositions are 2.35 and 21 µC/m 2 K, respectively. The piezoelectric coefficient values (d 33 ) for both the compositions are 0.9 and 1 pC/N, respectively. The observed values of electrical parameters closely resemble with that of the natural human bone.

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Growth of calcium phosphate on poling treated ferroelectric BaTiO3 ceramics

Cited by 55 publications

References 14 publications

Medical Application of Calcium Orthophosphate Bioceramics

Medical Application of Calcium Orthophosphate Bioceramics

Calcium Orthophosphates as Bioceramics: State of the Art

Dielectric and Pyroelectric Properties of HAp-BaTiO₃Composites

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Growth of calcium phosphate on poling treated ferroelectric BaTiO3 ceramics

Cited by 55 publications

References 14 publications

Medical Application of Calcium Orthophosphate Bioceramics

Medical Application of Calcium Orthophosphate Bioceramics

Calcium Orthophosphates as Bioceramics: State of the Art

Dielectric and Pyroelectric Properties of HAp-BaTiO3Composites

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Product

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About

Dielectric and Pyroelectric Properties of HAp-BaTiO₃Composites