Growth patterns of gastric carcinoma detected by mass survey

Abstract

Two hundred and sixty-seven cases of gastric carcinoma detected by mass survey included 196 discovered at the first examination (Group A) and 71 noted at the annual sequential examination (Group B) were analyzed in terms of growth pattern and prognosis. The incidence of early carcinoma was 54.9 per cent in Group B higher than 35.7 per cent in Group A. In early carcinoma, the superficially spreading (SUPER) type of carcinoma was more common in Group A than in Group B. On the contrary, the penetrating growth (PEN) type of carcinoma was more frequently found in Group B than in Group A. About eighty per cent of those with an advanced carcinoma, in both groups, was the advanced PEN type. The outcome of the patients in Group B was more favorable. These results support the hypothesis that the majority of advanced carcinoma is derived from the PEN type of early carcinoma. Early detection of the PEN type of carcinoma is mandatory.

A clinicopathological study of gastric cancer with special reference to age of the patients: An analysis of 1,630 cases

“…Consequently, resectability in the aged was lower than that of middle-aged patients. Several authors noted that the proportion of curative operation decreases with age [8,11], although that was not evident in this study.…”

“…That well-differentiated adenocarcinoma becomes predominant with age is well known aStages were determined by the histologic findings. [2,8,10,11,[13][14][15]. A striking difference was also noted in this study.…”

“…The male-to-female ratio was around 1:1 in young patients and it increased with age up to 3.46:1 in the 80 years of age or older group. This tendency, as recognized by many authors [2][3][4][5][6][7][8], may be relevant to the fact that sex hormones influence the growth of gastric cancer experimentally [9]. Tumors located in the lower third of the stomach increased in number with age, as reported previously [2,3,8,10,11], although some investigators reported opposite results [12,13].…”

“…This tendency, as recognized by many authors [2][3][4][5][6][7][8], may be relevant to the fact that sex hormones influence the growth of gastric cancer experimentally [9]. Tumors located in the lower third of the stomach increased in number with age, as reported previously [2,3,8,10,11], although some investigators reported opposite results [12,13]. That well-differentiated adenocarcinoma becomes predominant with age is well known aStages were determined by the histologic findings.…”

Effect of periodic endoscopy for gastric cancer on early detection and improvement of survival

“…This finding indicates that the optimal interval between gastric endoscopic screenings is 2 years. Some gastric cancers grow extremely rapidly and are highly malignant [11][12][13][14]. Detection of this type of tumor at an early phase of development is very difficult, and the usual screening test is relatively ineffective.…”