Growth Patterns of Thai Children with Down Syndrome from Birth to 5 Years

Abstract

Specific growth charts for children with Down syndrome (DS) have been developed in several countries, but not in Thailand. This pilot study aims to develop growth patterns for Thai children with DS, which will help clinicians to improve assessment and monitoring of the growth patterns for these children. A retrospective review of 80 children with DS who received care at Thammasat University Hospital between 2014 and 2018 was conducted. A total of 1,681 length/height and weight measurements were collected. Four sex-specific growth patterns of length/height and weight were generated with the fifth, 50th, and 95th percentile. The children with DS were lower in weight and shorter than general Thai children and children with DS in other countries. Therefore, each country should develop individual DS growth charts.

Status Antropometri pada Anak dengan Sindrom Down di Indonesia: Kurva Sindrom Down versus Kurva Internasional

“…Hal ini sesuai dengan penelitian yang dilakukan Bertapelli dkk 19 tahun 2017 di Brazil yang menemukan bahwa terdapat perbedaan bermakna nilai z-score tinggi badan kurva sindrom Down bila dibandingkan dengan kurva WHO. Hal ini juga sesuai dengan temuan penelitian yang dilakukan di Thailand bahwa terdapat perbedaan bermakna pada z-score 20 Penelitian-penelitian tersebut menemukan bahwa tingkat pertumbuhan anak dengan sindrom Down jauh dibawah standar WHO sehingga kurva WHO kurang sesuai digunakan untuk mengukur pertumbuhan anak dengan sindrom Down.…”

“…Temuan ini sesuai dengan hasil dengan penelitian di Amerika, Thailand, Brazil, dan Belanda yang membandingkan kurva sindrom Down dan kurva internasional sebelumnya. 12,[19][20][21] Penelitian di Amerika menyimpulkan bahwa anak dengan sindrom Down cenderung mengalami gangguan pertumbuhan panjang dan tinggi badan, terutama pada anak laki-laki. 12 Hal ini mengakibatkan adanya perbedaan bermakna interpretasi tinggi badan menggunakan kurva sindrom Down dan kurva anak normal.…”

Down Sendromlu Çocuklarda Ve Tipik Gelişim Gösteren Akranlarında Vücut Kitle İndeksi, Q Açısı Ve Pes Planus Yürüme Yaşını Etkiler Mi?

“…It is characterized by structural, mental and organismal changes that cause mental retardation and delay in motor performance. Often these changes are accompanied by a range of medical problems, including cardiac and respiratory problems (2,3). Although the incidence varies by ethnicity and geographic region, DS occurs in about 1 in 800 births worldwide (4).…”