Growth Performance, Antioxidant Capacity, Lipid-Related Transcript Expression and the Economics of Broiler Chickens Fed Different Levels of Rutin

Abstract

Simple SummaryPoultry makes a substantial contribution to food security and nutrition. A growing human population and rising incomes have resulted in an increased demand for white meat. Poultry is the fastest growing animal production sector. Rutin, a natural growth and health promoter, was used at three levels for broiler feed (0.25, 0.5 or 1 g rutin/kg). Supplementing broiler diets with rutin, especially at 1 g/kg, has a variety of growth-promoting effects. It enhances antioxidant capacity and suppresses lipogenesis, thereby reducing fat deposition and serum lipid levels. The results demonstrate that the observed benefits can be achieved without compromising economic profits.AbstractThe effects of rutin on growth performance, hematological and biochemical profiles, antioxidant capacity, economics and the relative expression of selected antioxidants and lipid-related genes were studied in broiler chickens over 42 days. A total of 200 one-day-old female Ross-308 broiler chickens were distributed into four groups, with five replicates of 10 individuals per replicate. They were fed with 0 (control), 0.25, 0.5 or 1 g rutin/kg supplementation in their basal diet. Dietary rutin supplementation, especially the 1 g/kg diet, increased body weight gain, the protein efficiency ratio (p < 0.001) and both white blood cell and lymphocyte counts (p < 0.001). However, it had no effect on total protein, albumin, globulin, or alanine transaminase. A high concentration of rutin (0.5 and 1 g/kg) also significantly reduced serum total cholesterol, triacylglycerol and low-density lipoprotein cholesterol concentrations (p < 0.001), as well as malondialdehyde concentrations (p = 0.001). A high concentration diet also increased the activity of superoxide dismutase, catalase and glutathione peroxidase. Of the lipid-related genes examined, acetyl CoA carboxylase and fatty acid synthase were significantly down-regulated in the livers of rutin-fed individuals, whereas carnitine palmitoyl transferase 1 and peroxisome proliferator-activated receptor alpha were significantly up-regulated. Therefore, rutin supplementation at 1 g/kg has the potential to improve the productive performance and health status of broiler chickens.

Synergism of Dietary Co-Supplementation with Lutein and Bile Salts Improved the Growth Performance, Carotenoid Content, Antioxidant Capacity, Lipid Metabolism, and Lipase Activity of the Marbled Spinefoot Rabbitfish, Siganus rivulatus

“…In addition. Lutin supplementation reduced serum total cholesterol, triacylglycerol levels in Broiler Chickens [88].…”

The Effect of Dietary Garlic (Allium Sativum), Black Cumin (Nigella Sativa) and Their Combination on Performance, Intestine Morphometry, Serum Biochemistry and Antioxidant Status of Broiler Chickens

“…In recent years many scientist showed interest in researches about oxidative stress and antioxidant agents. Among these antioxidant agents natural substances attracted most of the attention because these substances can prevent diseases and positively affect the health (Hassan et al, 2018). The efficacy of garlic preparations or extracts to alleviate free radical damage to biological membranes or other biological systems has been demonstrated (Horie et al, 1989;Knasmüller et al, 1989;Kourounakis & Rekka, 1991;Chung, 2006).…”

Effect of polyphenol extract on performance, serum biochemistry, skin pigmentation and carcass characteristics in broiler chickens fed with different cereal sources under hot-humid conditions

“…Use of active compounds of phytogenic origin has received extensive attention due to their wide spectrum of functions. Studies with polyphenols revealed that the addition of phenolic compounds improved the performance and feed efficiency ( Hassan et al, 2019 ). These polyphenols are mainly concentrated on the pericarp/outer protective layers of fruit or seed.…”