Growth Promoters and Novel Feed Additives Improving Poultry Production and 
 Health, Bioactive Principles and Beneficial Applications: The Trends and Advances-A 
 Review

Dhama, Kuldeep; Tiwari, Ruchi; Khan, Rifat Ullah; Chakrabort, Sandip; Gopi, M.; Karthik, Kumaragurubaran; Saminathan, Mani; Desingu, Perumal Arumugam; Sunkara, Lakshmi T.

doi:10.3923/ijp.2014.129.159

Cited by 129 publications

(112 citation statements)

References 144 publications

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“…These compounds are being replaced because current trends indicate that consumers are increasingly rejecting the use of synthetic substances in food production; therefore, plant-derived compounds with growth-promoting activity, also known as phytogenic compounds, are gaining a presence in the feed additive market [11, 22]. …”

Section: Phytochemicals As An Alternative To Animal Growth Promoters:mentioning

confidence: 99%

Dietary inclusion effects of phytochemicals as growth promoters in animal production

et al. 2017

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Growth promoters have been widely used as a strategy to improve productivity, and great benefits have been observed throughout the meat production chain. However, the prohibition of growth promoters in several countries, as well as consumer rejection, has led industry and the academy to search for alternatives. For decades, the inclusion of phytochemicals in animal feed has been proposed as a replacement for traditional growth promoters. However, there are many concerns about the application of phytochemicals and their impact on the various links in the meat production chain (productive performance, carcass and meat quality). Therefore, the effects of these feed additives are reviewed in this article, along with their potential safety and consumer benefits, to understand the current state of their use. In summary, the replacement of traditional growth promoters in experiments with broilers yielded benefits in all aspects of the meat production chain, such as improvements in productive performance and carcass and meat quality. Although the effects in pigs have been similar to those observed in broilers, fewer studies have been carried out in pigs, and there is a need to define the types of phytochemicals to be used and the appropriate stages for adding such compounds. In regard to ruminant diets, few studies have been conducted, and their results have been inconclusive. Therefore, it is necessary to propose more in vivo studies to determine other strategies for phytochemical inclusion in the production phases and to select the appropriate types of compounds. It is also necessary to define the variables that will best elucidate the mechanism(s) of action that will enable the future replacement of synthetic growth promoters with phytochemical feed additives.

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Section: Phytochemicals As An Alternative To Animal Growth Promoters:mentioning

confidence: 99%

Dietary inclusion effects of phytochemicals as growth promoters in animal production

et al. 2017

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“…The heightened public concern over the emergence of antibiotic‐resistant strains prompted the exploitation of alternate growth promoters to antibiotics (Dhama et al, ; Yadav et al, ). Among such alternatives, one such striking preference includes acidifiers, especially in swine and poultry sectors.…”

Section: Introductionmentioning

confidence: 99%

Role of acidifiers in livestock nutrition and health: A review

Pearlin

Shanmathy

Govidasamy

et al. 2020

Animal Physiology Nutrition

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135

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Ever since the European ban on use of in‐feed antibiotics in food animals, the search for alternate antibiotic‐free growth promoter is undertaken worldwide. There are few alternatives such as probiotics, pre‐biotics, phytochemicals, enzymes and organic acids. Among these alternatives, the organic acids or simply acidifiers play an important role in gut health in animals. The acidifiers could be used to favourably manipulate the intestinal microbial populations and improve the immune response, hence perform an activity similar to antibiotics in food animals in countering pathogenic bacteria. Acidifiers also improve the digestibility of nutrients and increase the absorption of minerals. The incorporation of organic acids also leads to thinning of the intestinal lining which facilitates better absorption of nutrients and its efficient utilization. However, their effect will not be similar among all types of organic acids as their mechanism of activity is based on its pKa value. Moreover, there are claims about the neutralization of acids by the secretion of bicarbonates in the initial part of intestine, reactivity with metallic items in feed mills and reduced palatability due its bitter taste demands non‐reactive and targeted delivery for better performance. Currently, coated salts of acidifiers are available commercially for use in food animals especially pigs and poultry. The present review highlights the role of different acidifiers in livestock nutrition with their potent applications in improving nutrient digestibility, mineral utilization, meat quality, enhancing immunity, antimicrobial effects in countering pathogenic bacteria, boosting performance and production, and thus safeguarding health of livestock animals and poultry.

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“…The addition of various nutritional supplements and additives to foods/diets including growth promoters, antioxidants, nutraceuticals, herbs, green tea, coffee, probiotics and others for enhanced production performances, improved immunity, and health benefits in humans, animals, poultry, and other species is showing an increasing trend Dhama, Tiwari, Chakrabort, et al, 2014;Dhama, Tiwari, Khan, et al, 2014;Laudadio et al, 2015;Mahima et al, 2013;Suez, Zmora, Segal, & Elinav, 2019;Xing, Zhang, Qi, Tsao, & Mine, 2019). Particularly, plants, herbs and shrubs that possess high medicinal values have attracted the attention of worldwide researchers owing to their multiple beneficial health applications (Abd El-Hack & Alagawany, 2015;Alagawany et al, 2019;Mahima et al, 2012;Tiwari et al, 2018;Velmurugan, Kalpana, Cho, & Lee, 2018;Yatoo et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Nutritional applications and beneficial health applications of green tea and l‐theanine in some animal species: A review

Alagawany

El‐Hack

Saeed

et al. 2019

Animal Physiology Nutrition

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Green tea (Camellia sinensis) is a popular herbal plant with abundant health benefits, and thus, it has been used as a potent antioxidant for a long time. Based on the available literature, the diversity and the availability of multifunctional compounds in green tea offer its noteworthy potential against many diseases such as liver and heart diseases, inflammatory conditions and different metabolic syndromes. Owing to its bioactive constituents including caffeine, amino acids, l-theanine, polyphenols/ flavonoids and carbohydrates among other potent molecules, green tea has many pharmacological and physiological effects. The effects of green tea include anti-oxidative, anti-inflammatory, anti-arthritic, anti-stress, hypolipidaemic, hypocholesterolaemic, skin/collagen protective, hepatoprotective, anti-diabetic, anti-microbial, anti-infective, anti-parasitic, anti-cancerous, inhibition of tumorigenesis and angiogenesis, anti-mutagenic, and memory and bone health-improving activities. Apart

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Growth Promoters and Novel Feed Additives Improving Poultry Production and Health, Bioactive Principles and Beneficial Applications: The Trends and Advances-A Review

Cited by 129 publications

References 144 publications

Dietary inclusion effects of phytochemicals as growth promoters in animal production

Dietary inclusion effects of phytochemicals as growth promoters in animal production

Role of acidifiers in livestock nutrition and health: A review

Nutritional applications and beneficial health applications of green tea and l‐theanine in some animal species: A review

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