Growth references for height, weight, and head circumference for Argentine children with achondroplasia

Abstract

references presented here can also be used in other countries with similar ethnographics characteristics.

Growth in achondroplasia: Development of height, weight, head circumference, and body mass index in a European cohort

“…Despite differences in height of background populations, ages for reporting adult height and data collection periods, adult height is remarkably similar between achondroplasia growth studies (Table ). Exceptions might be recent U.S. (Hoover‐Fong et al, ) and Argentinian references (Del Pino et al, ), although, it is not clear whether final adult height was captured in these studies. Adult height in a recently published U.S. report (Hoover‐Fong et al, ) is clearly lower than in previous U.S. studies (Horton et al, ; Murdoch et al, ).…”

“…An activating mutation of the FGFR3 (fibroblast growth factor receptor 3) causes major growth inhibition of the extremities and thus extreme short stature in achondroplasia. Growth in achondroplasia has been described by several authors (Murdoch et al, ; Nehme, Riseborough, & Tredwell, ; Wynne‐Davies, Walsh, & Gormley, ) and growth curves have been published from the United States (Hoover‐Fong, McGready, Schulze, Alade, & Scott, ; Hoover‐Fong, McGready, Schulze, Barnes, & Scott, ; Hoover‐Fong, Schulze, McGready, Barnes, & Scott, ; Horton, Rotter, Rimoin, Scott, & Hall, ), Japan (Tachibana, Suwa, Nishiyama, & Matsuda, ), Argentina (Del Pino, Fano, & Lejarraga, ), and Australia (Tofts, Das, Collins, & Burton, ). However, there are no recent European growth curves.…”

Height growth velocity during infancy and childhood in achondroplasia

“…In comparison with growth velocities of non-ACH children from the United States, in a sample processed with the same mathematical method, the growth velocity of ACH-children was lesser in magnitude (Berkey & Reed, 1987). This growth retardation during infancy, determine the severe growth deficit at 2 years of age for ACH children described in different populations (del Pino et al, 2010;Hoover-Fong et al, 2017;Merker et al, 2018;Tofts et al, 2017).…”

“…During infancy and childhood height falls progressively and in adolescents, is approximately 5.00 SDS below the 50th centile for Argentine and others non-ACH populations with a mean adult height of −6.42 and −6.72 SDS, for males and females, respectively (del Pino et al, 2010;Hoover-Fong, McGready, Schulze, Alade, & Scott, 2017;Lejarraga, del Pino, Fano, Caino, & Cole, 2009;Merker et al, 2018;Tofts, Das, Collins, & Burton, 2017).…”

“…Cross sectional design studies of growth show that ACH children are born disproportioned (mean sitting height/height ratio + 5 SDS) and shorter (mean birth length −2.5 SDS) than non-ACH children (del Pino, Fano, & Lejarraga, 2010;del Pino, Ramos Mejía, & Fano, 2018).…”