Researchers in Information Systems have produced a rich collection of meta-analyses and models to further understanding of factors influencing the uptake of information technologies. In the domain of CSCW, however, these models have largely been neglected, and while there are many case studies, no systematic account of uptake has been produced. We use findings from Information Systems research to structure a meta-analysis of uptake issues as reported in CSCW case studies, supplemented by a detailed re-examination of one of our own case studies from this perspective. This shows that while there are some factors which seem to be largely specific to CSCW introductions, many of the case study results are very similar to standard IS findings. We conclude by suggesting how the two communities of researchers might build on each other’s work, and finally propose activity theory as a means of integrating the two perspectives.