Guaiane sesquiterpenes from agarwood

Ishihara, Masakazu; Tsuneya, Tomoyuki; Uneyama, Kenji

doi:10.1016/0031-9422(91)83206-z

Cited by 75 publications

(60 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previously, four compounds have been reported from agarwood, β-gurjunene (Ishihara and Tsuneya 1993a ;Wetwitayaklung et al 2009 ), γ-selinene (Wetwitayaklung et al 2009 ), α-guaiene (Ishihara et al 1991b ), and α-bulnesene (Ishihara and Tsuneya 1993a ;Wetwitayaklung et al 2009 ), similar to our fi ndings.…”

Section: Discussionsupporting

confidence: 93%

Resolution of Complex Sesquiterpene Hydrocarbons in Aquilaria malaccensis Volatile Oils Using Gas Chromatography Technique

2016

View full text Add to dashboard Cite

Agarwood or gaharu is resin-impregnated wood of the tree genus Aquilaria (Thymelaeaceae). In Malaysia, the main agarwood producer is Aquilaria malaccensis and oil extracted from this species is highly priced. One of the challenges in commercializing agarwood is the lack of universal standard to classify the aromatic oils. Our present knowledge places the main aromatic compounds of agarwood oil in the sesquiterpene hydrocarbon region. In this work, we extracted agarwood oil using hydrodistillation method in the laboratory and compared with a commercial-scale extraction in the factory. We analyzed the sesquiterpene hydrocarbon region using several highly sophisticated detection systems. Using GC-FID, 12 sesquiterpene hydrocarbons were identifi ed, while another eight were determined using GC-MS. Five compounds were identifi ed in both analytical techniques: aromadendrene, α-bulnesene, α-guaiene, γ-gurjunene, and β-maaliene. Advanced analysis using GC × GC/TOFMS detected 24 sesquiterpene hydrocarbons in both laboratory and pilot scale agarwood oils. Many of the sesquiterpene hydrocarbons identifi ed provide the woody aroma to the agarwood oil. Specifi cally, α-gurjunene and α-guaiene contribute to the woody balsamic aroma, while α-copaene contributes to the spicy-wood aroma. In total, 33 sesquiterpene hydrocarbons were identifi ed from A. malaccensis in the present study, with high certainty. Results from this study can be used toward establishing a universal standard for agarwood oil from the genus Aquilaria in the global market, which is presently lacking.

show abstract

Section: Discussionsupporting

confidence: 93%

Resolution of Complex Sesquiterpene Hydrocarbons in Aquilaria malaccensis Volatile Oils Using Gas Chromatography Technique

2016

View full text Add to dashboard Cite

show abstract

“…Although earlier literature concentrated on the phytochemistry of the resinous wood, and to some extent the oil produced from the resinous wood (Ishihara et al, 1991a;Ishihara et al, 1991b;Jain, 1959;Nakanishi et al, 1981;Nakanishi et al, 1983;Nakanishi et al, 1984;Varma et al, 1965;Yoneda et al, 1984), the review literature on current work related to the compounds and bioactivities of the different parts of the agarwood plant is very limited, with existing publications focused on specific species, namely, Aquilaria agallocha (Alam, 2015) and Aquilaria sinensis . Another review attempted to report the pharmacological properties of Aquilaria spp., but provided limited information (Jok, 2015).…”

Section: Discussionmentioning

confidence: 98%

“…Earlier publications reflect the fact that agarwood resin constituents were isolated using solvent extraction, with subsequent purification via column chromatography and structural elucidation using spectroscopic techniques, including NMR (Bhandari et al, 1982;Ishihara et al, 1991a;Ishihara et al, 1991b;Jain, 1959;Nakanishi et al, 1986;Nakanishi et al, 1981;Nakanishi et al, 1983;Nakanishi et al, 1984;Yoneda et al, 1984). More recent articles focus on the use of the 'hyphenated' techniques to detect and identify compounds.…”

Section: Resin and Essential Oilmentioning

confidence: 98%

Aquilaria spp. (agarwood) as source of health beneficial compounds: A review of traditional use, phytochemistry and pharmacology

Hashim

Kerr

Abbas

et al. 2016

Journal of Ethnopharmacology

180

127

View full text Add to dashboard Cite

“…In 2011, researchers found 15 species of agarwood [6]. The Aquilaria Malaccensis has a big population in Malaysia forest [7] and Aquilaria Agallocha Roxb is originately found in Japan [8]. In Japan, the wood is called according to their quality, Kanankoh for high quality and Jinkoh for low [8][9][10].…”

Section: Introductionmentioning

confidence: 98%

Investigation of common compounds in high grade and low grade Aquilaria Malaccensis using correlation analysis

Ismail

Rahiman

Jailani

et al. 2012

2012 IEEE Control and System Graduate Research Colloquium

View full text Add to dashboard Cite

This paper presents a correlation analysis between high grade and low grade of Aquilaria Malaccensis (AM). Seven selected samples of AM were identified using Gas Chromatograph -Mass Spectra (GC-MS) and several statistical techniques have been employed. The samples were separated into two grades such as high grade and low grade. The analysis involves of normality test such as Shapiro Wilk, standard deviation, skewness, kurtosis and correlation analysis. All the analysis was done using SPSS ver. 15.0. The result shows that there are no significant correlation between high grade and low grade and it is a high correlation among compounds in similar grade. Three common compounds and highly correlated found in both grade and they are hexadecanoic acid, valencene and α-guaiene.

show abstract

Guaiane sesquiterpenes from agarwood

Cited by 75 publications

References 4 publications

Resolution of Complex Sesquiterpene Hydrocarbons in Aquilaria malaccensis Volatile Oils Using Gas Chromatography Technique

Resolution of Complex Sesquiterpene Hydrocarbons in Aquilaria malaccensis Volatile Oils Using Gas Chromatography Technique

Aquilaria spp. (agarwood) as source of health beneficial compounds: A review of traditional use, phytochemistry and pharmacology

Investigation of common compounds in high grade and low grade Aquilaria Malaccensis using correlation analysis

Contact Info

Product

Resources

About