Guaiane sesquiterpenes from seaweed Ulva fasciata Delile and their antibacterial properties

Controlling of Microbial Growth by Using Cystoseira barbata Extract

“…Phenols have been identified in several algal species as biologically active compounds (Vairappan, et al, 2001). Many compounds of marine algae show anti-bacterial activities as polysaccharide (Laurienzo, 2010), lyengaroside (Ali et al, 2002), polyhydroxy lated fucophlorethol (Sandsdalen et al, 2003), bromophenols (Oh et al, 2008), guaiane sesquiterpene (Chakraborty & Lipton, 2010), lactone malyngolide (Cardelina et al, 1979) cycloeudesmol (Sims et al, 1975), polyphenolic compound (Devi, 2008), halogenated compound (Vairappan, 2003) and quinone metabolite (Horie et al, 2008). Flavonoids comprise a large group of naturally compounds widely distributed in the algae and some of these compounds have been reported to contain various and potent biological activities including anti oxidative tissue protective and tumoristatic effects as well as the inhibition of hepatic cholesterol biosynthesis (Krant et al, 2005;Kim et al, 2007;Matanjun et al, 2008 andVolk, 2009).…”

The Marine Macroalgae of the Genus Ulva: Chemistry, Biological Activities and Potential Applications

“…Among all macroalgae, the green algae with less than 300 known compounds are the least producers of natural compounds when compared to the red (Rhodophyta) and brown algae (Phaeophyta) [9,10]. Anyhow, a wide range of compounds, predominantly terpenes, polyphenols and steroids, have been reported in various marine green algae [11,12]. The chemical composition of these macroalgae was found to vary depending on geographical distribution and seasons and the principal environmental factors affecting the composition being water temperature, salinity, light, nutrients and minerals availability [5].…”

“…By using gas chromatography coupled to mass spectrometry (GC-MS), Flodin and Whitfield were able to detect 2,4,6-tribromophenol (1) ( Figure 1) from the crude extract of U. lactuca [13], collected in Turimetta Head, North of Sydney, on the Eastern coast of Australia. Later, 3-O-β-D-glucopyranosylstigmasta-5,25-diene (2) (Figure 1) was isolated from the methanol extract of U. lactuca, collected from the coast of Alexandria, Egypt [12,14,15]. Using High Performance Liquid Chromatography (HPLC), the Chinese group was able to isolate five nor-isoprenoids: (3S,5R,6S,7E) 3,5,6-trihydroxy-7-megastigmen-9-one (3), (3R,5R,6R,7E) 3,5,6-trihydroxy-7-megastigmen-9-one (4), (3S,6R) 3,6-dihydroxy-4,7-megastigmadien-9-one (5), grasshopper ketone (6), and isololiolide (7) (Figure 1), from the methanol extract of U. lactuca, collected off the coast of Bohai in China [16].…”

“…of U. fasciata Delile, collected in Vizhinjam and Mullur in Kerala, India [12]. From the methanol extract of the same species collected in the same local, Chakraborty and Paulraj have reported isolation of five sesquiterpenes: 2,5,5-trimethyl-4-(4´-methyl-3´-pentenyl)-2-cyclohexen-1-ol (21), 4-isopentyl-3,4,5,5-tetramethyl-2-cyclohexen-1-ol (22, two diastereoisomeric compounds), 6-isopentyl-1,5,5,6-tetramethyl-1-cyclohexene (23), and 3,4,5,5-tetramethyl-4-(3´-oxopentyl)-2-cyclohexen-1-one (24) (Figure 4) [17].…”

Protective role of marine macroalgae extracts against STZ induced diabetic rats

“…Seaweeds are group of non-flowering marine plants commonly known as macroalgae having increased demand in cosmetic, pharmaceutical and food additives [8,9]. They are photosynthesizing organisms in marine environment and produce the basic biomass in the intertidal zone and have a rich source of bioactive compounds, such as carotenoids, proteins, oligosaccharides, essential fatty acids, antioxidants, vitamins and minerals useful in medical and pharmaceutical industries [10][11][12].…”