Guest Edited Collection: Radioisotopes and radiochemistry in health science

Abstract

Radioisotopes can be produced artificially from stable nuclei through the interaction with particles or highly energetic photons. In combination with modern detection and counting techniques, radioisotopes and radiochemical methods uniquely contribute to the health sciences. This Collection showcases salient aspects of medical radioisotope science ranging from the production, recovery and purification of radioisotopes to the methods used to attach them to biomolecules. The Collection also presents studies that highlight the importance of radiochemistry in the assessment of environmental radioactivity.

ASTRO's Framework for Radiopharmaceutical Therapy Curriculum Development for Trainees

“…Fassbender 81 Pharmacokinetics Sparreboom 82 Sunderland 83 Abbreviations: PGY = postgraduate year; RPT = radiopharmaceutical therapy.…”

Radiolabeling Strategies of Nanobodies for Imaging Applications

“…In contrast, copper-64 and zirconium-89 constitute radiometals with supplemental alternative decay pathways, requiring higher administration doses because of lower sensitivity. Additionally, both radionuclides have much longer half-lives (12.7 h for copper-64 [ 55 ]; 78.4 h for zirconium-89 [ 56 ]), rendering them less appropriate for nanobody radio imaging. This also applies to the gamma-emitting radiometals indium-111 and lutetium-177, which possess a half-life of 67.2 h [ 57 ] and 6.65 days [ 58 ], respectively.…”

Leveraging Calibration Transfer Techniques for Remote Monitoring of Samarium and Europium in LiCl Using Laser-Induced Florescence Spectroscopy for Radioisotope Production Applications

“…Radioisotopes are critical resources for a plethora of applications, including radiopharmaceuticals, industrial radiography, powering deep-space exploration, and neutron sources. 1 The isotope 252 Cf is used as a neutron source for nuclear reactor start-up, neutron activation analysis, and oil field exploration. 2 This 252 Cf is produced at Oak Ridge National Laboratory by irradiating 249 Bk with neutrons in the High Flux Isotope Reactor, after which the targets are processed to separate the 252 Cf, as well as other isotopes, and recover the remaining 249 Bk for further use.…”

“…Radioisotopes are critical resources for a plethora of applications, including radiopharmaceuticals, industrial radiography, powering deep-space exploration, and neutron sources . The isotope 252 Cf is used as a neutron source for nuclear reactor start-up, neutron activation analysis, and oil field exploration .…”