Guided fine needle aspiration cytology of retroperitoneal masses - Our experience

Abstract

Background:Early pathological classification of retroperitoneal masses is important for pin-point diagnosis and timely management.Aims:This study was done to evaluate the usefulness and drawbacks of guided fine needle aspiration cytology (FNAC) of retroperitoneal masses covering a period of two years with an intention to distinguish between neoplastic and non-neoplastic lesions and to correlate with histologic findings.Materials and Methods:FNAC was done under radiological guidance in all cases using long needle fitted with disposable syringe. Appropriate staining was done and cytology was correlated with histology which was taken as the gold standard for comparison.Results:Fifty-one patients who presented with retroperitoneal masses were studied. Forty-four lesions were malignant cytologically and 7 were inflammatory (tuberculous). According to radiological and cytologic findings, we classified our cases into four groups: renal tumors, retroperitoneal lymphadenopathy, germ cell tumors, soft tissue tumors. Except for cases of non-Hodgkin lymphoma (NHL) and metastatic lesions, we had sensitivity and specificity of 100%. In NHL the sensitivity and specificity were both 50%. In cases of metastatic adenocarcinoma, the sensitivity and specificity were 84.6% and 81.8%, respectively.Conclusions:Ignoring the pitfalls, guided FNAC is still an inexpensive and reliable method of early diagnosis of retroperitoneal lesions.

Retroperitoneal Tumor: A Silent Trespasser – Role of Image-Guided Fine-Needle Aspiration Cytology with Histopathological Correlation in Early Diagnosis

“…The most common nonneoplastic lesion was tubercular lymphadenitis ( n = 12; 42.85%), which is similar to the findings of Ahmad et al [5] ( n = 12; 60%), Mangal et al[1] ( n = 6 cases; 22%), and Gangopadhyay et al [3] ( n = 7; 13.72%).…”

“…In the current study, most retroperitoneal masses were malignant ( n = 274; 88.4%), which is similar to the findings of Gangopadhyay et al [3]. They reported 7 cases (13.72%) as benign and nonneoplastic and 44 cases (86.27%) as malignant lesions, and Mehdi et al [4] reported 11 cases (28.94%) as benign and nonneoplastic and 27 cases (71.05%) as malignant.…”

“…Of the total of 8 benign lesions, most were paraganglioma ( n = 3; 37.5%), which is similar to the findings of Gangopadhyay et al [3]. They noted 1 case of paraganglioma as the only benign lesion.…”

“…However, Gangopadhyay et al [3] found a retroperitoneal lymph nodal origin to be the most common ( n = 20; 39.21%).…”

Endoscopic/Endobronchial Ultrasound-Guided Fine Needle Aspiration and Ancillary Techniques, Particularly Flow Cytometry, in Diagnosing Deep-Seated Lymphomas

“…In our institution, we prefer to stain smeared slides (80%) with the Romanowsky stain (Diff-Quik) if a hematopoietic lineage is determined at the time of ROSE. However, the distinction may not always be straightforward [43,44]. Lymphoma cells may artificially show ‘pseudocohesion', especially in highly cellular specimens, and some poorly differentiated nonlymphoid malignancy may show a predominant pattern of dispersion.…”