I would not be here writing this PhD Thesis without the support of all the people who have walked next to me for four years.First of all, I would like to deeply thank my supervisors, Professor Javier Martí Sendra and Dr Jaime García Rupérez, as well as my academic tutor Dr Mª José Bañuls Polo, for the opportunity they gave me to get involved in the world of biophotonics and biosensors. Specially to Jaime, who guided me along this way and supported me whenever I needed. Thank you for all the opportunities you gave me to gain experience and experiences in this scientific and academic world.I would also like to thank all the wonderful people I found at NTC. In particular, the Biophotonics group members for making things easier: Ángela,